Synthesis, Characterization, Corrosion Resistance and In-Vitro Bioactivity Behavior of Biodegradable Mg–Zn–Mn–(Si–HA) Composite for Orthopaedic Applications

Abstract

Recently, magnesium (Mg) has gained attention as a potential material for orthopedics devices, owing to the combination of its biodegradability and similar mechanical characteristics to those of bones. However, the rapid decay rate of Mg alloy is one of the critical barriers amongst its widespread applications that have provided numerous research scopes to the scientists. In this present, porous Mg-based biodegradable structures have been fabricated through the hybridization of elemental alloying and spark plasma sintering technology. As key alloying elements, the suitable proportions of silicon (Si) and hydroxyapatite (HA) are used to enhance the mechanical, chemical, and geometrical features. It has been found that the addition of HA and Si element results in higher degree of structural porosity with low elastic modulus and hardness of the Mg–Zn–Mn matrix, respectively. Further, addition of both HA and Si elements has refined the grain structure and improved the hardness of the as-fabricated structures. Moreover, the characterization results validate the formation of various biocompatible phases, which enhances the corrosion performance and biomechanical integrity. Moreover, the fabricated composites show an excellent bioactivity and offer a channel/interface to MG-63 cells for attachment, proliferation and differentiation. The overall results of the present study advocate the usefulness of developed structures for orthopedics applications.

The Potential of Magnesium Based Materials in Mandibular Reconstruction

“…Presence of calcium in the form of supplements could also assist with osteoblast activity, leading to easier bone remodeling activity [68,110]. Prakash et al [111] studied the effect of Si and HA addition to the corrosion resistance and in vitro bioactivity behavior of Mg-Zn-Mn alloy using MG-63 osteoblast cells. With increased incubation times, Mg-Zn-Mn-(Si-HA) bio composite showed increased cell and proliferation when compared to Mg-Zn-Mn alloy.…”

Surface Modification of Ti-6Al-4V Alloy by Electrical Discharge Coating Process Using Partially Sintered Ti-Nb Electrode

“…The EDS spectrum confirms the presence of Ti and Nb elements. Apart from the presence of base metal elements, the element O (possible oxides) was noticed as well on the surface, which is a common observation in the SPS-treated surface [35,36,37,38,39,40]. Figure 3d shows the associated XRD pattern of the sintered Ti-Nb alloy and endorses the phase composition of the sample at the different sintering temperature.…”

Carbon Nanotubes (CNTs)-Reinforced Magnesium-Based Matrix Composites: A Comprehensive Review

“…The advantageous properties could be attained only if the reinforcements are distributed homogeneously and not clustered in the matrix. According to the literature available [ 153 , 154 , 155 , 156 , 157 , 158 , 159 , 160 , 161 , 162 , 163 , 164 , 165 , 166 , 167 , 168 , 169 , 170 , 171 , 172 , 173 , 174 , 175 , 176 , 177 , 178 , 179 , 180 , 181 , 182 , 183 , 184 , 185 , 186 , 187 ], limited research has been performed on CNT-reinforced MMCs due to difficulties in fabricating and dispersion of CNTs in the matrix. Most studies investigated the fabrication methods such as the casting process and powder metallurgy for developing Mg-based alloy [ 188 , 189 , 190 , 191 , 192 , 193 , 194 , 195 , 196 , 197 , 198 , 199 , 200 , 201 ,…”