Synthesis, Complexation and Characterization of 1-Phenyl-3-Methyl-4- (p-nitrobenzoyl) Pyrazolone-5(HNPz) and its complexes of Barium(II), Strontium(II) and Zinc(II)

Abstract

Complexes of Ba(II), Sr(II) and Zn(II) with 1-phenyl-3-methyl-4-(p-nitrobenzoyl) pyrazolone-5(HNPz) have been synthesized and characterized. The HNPz was prepared from high grade p-nitrobenzoyl chloride and 1-phenyl-3-methyl-5-pyrazolone. The process involved benzoylation of 17.60 g (0.10 M) 1-phenyl-3-methyl-5-pyrazolone (HPMP) with 14.55 g (0.103 M) nitrobenzoylchloride. The complexes of Ba (II), Sr (II) and Zn (II) were prepared by dissolving 5 mmol of BaCl 2 .2H 2 O,SrCl 2 .6H 2 O and ZnSO 4 .7H 2 O respectively in 10 mmol of HNPz. The complexing agent and the metal complexes were characterized by elemental analysis, UV-visible and infrared spectroscopies. The results show the complexes to be dihydrated bischelates conforming to a general molecular formula, MLn.2H 2 O, where L is the 4-acylpyrazolonato ion and n is the ligand number or oxidation state of metal,M (Ba, Sr, Zn). The study also indicates the formation of octahedral complexes which are presumed to have been formed through the enolic and carbonyl oxygen atoms of the coordination reagent; in which water molecules complete the expected coordination numbers of Ba(II), Sr(II) and Zn(II).

Eco-friendly 2-Thiobarbituric acid as a corrosion inhibitor for API 5L X60 steel in simulated sweet oilfield environment: Electrochemical and surface analysis studies

“…The use of corrosion inhibitors is the most practical and less expensive approach widely employed to control corrosion in the oil and gas industries 4–8 . Hitherto, arsenates, chromates, ferrocyanide, and metavandate were the choice corrosion inhibitors for the oilfield corrosion but have long lost patronage on the basis of their high toxicity.…”

Synthesis and Characterization of Bioactive Acylpyrazolone Sulfanilamides and Their Transition Metal Complexes: Single Crystal Structure of 4-Benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one Sulfanilamide

“…Acylpyrazolones are a series of heterocyclic diketones that have attracted a lot of research attention because of their chemistry and strong chelating properties especially towards transition metal ions [ 9 ] and numerous uses [ 10 ]. Knorr first synthesized pyrazolone derivatives by reacting phenyl hydrazine with ethylacetoacetate to form a novel 1-phenyl-3-methyl-5-pyrazolone in 1883 and studies on this group of compounds have been on since then [ 11 ]. They have the ability to exist either in an enol or keto tautomer forms, which gives them the potential to form different types of interesting coordination compounds [ 12 , 13 ].…”

Microwave-assisted synthesis of biologically relevant steroidal 17-exo-pyrazol-5'-ones from a norpregnene precursor by a side-chain elongation/heterocyclization sequence

“…Interestingly, so far only a few examples of compounds in which a pyrazolone moiety is attached to the sterane skeleton have been published, but not to C-17 [ 10 ]. Nevertheless, this heterocyclic scaffold is also an important building block in many clinically relevant drugs, agrochemicals, dyes, pigments and chelating agents [ 11 – 13 ], and therefore its introduction to C-17 of androstanes may be of interest from a pharmacological point of view.…”