Synthesis, crystal structure and antibacterial activity of zinc(II) complexes with Schiff bases derived from 5-fluorosalicylaldehyde

Liang, Xingxing; Zhao, Xinyi; Guo, Ang; Wang, Xiaowen; Rong, Mingzhe; Chang, Lin; Sun, Zhongqiao; Jin, Xudong

doi:10.1080/00958972.2023.2170795

Cited by 3 publications

(1 citation statement)

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“…Schiff bases (SBs) and their metal complexes have been widely investigated because of their biological activity (Liang, et al, 2023), (Shammout, et al, 2021). It is an important class of compounds containing the azomethine (>C=N-) linkage as a functional group, nitrogen bonds to the aryl or alkyl group but not to the hydrogen atom, and are excellent ligands that can coordinate and stabilize metal ions with various oxidation states (Yousif, et al, 2017), (Shah, et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization, and Bioactivity Studies of the Schiff Base Ligand and its Zinc(II) Complex

Muhammad Salih

2024

ARO

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One of the largest concerns to global health in recent decades has been identified as the growth of bacteria resistance to antibiotics. The Schiff base (SBs) and the zinc(II) SBs complex compounds category have attracted a lot of interest because of their function in chemical syntheses and their potential for bioactive and pharmacological effects. The present study includes the synthesis of various SBs with different substituents. Equimolar mixtures of benzaldehyde derivatives (1, 2) and aniline derivatives (3, 4) are used to carry out a series of condensation reactions to get compounds (5-7). By stoichiometrically combining Zn (II) acetate and ZnCl2 separately with the SBs ligand (7) in ethanol, it has been possible to prepare the SBs zinc(II) complex (8). The structure of the ligand and its metal complex are analyzed using (Fourier transform infrared spectroscopy, 1H-NMR, 13C-NMR) spectroscopy, scanning electron microscopy, and liquid chromatography–mass spectrometry. Moreover, the synthesized compounds are verified in vitro against Escherichia coli Gram negative, Staphylococcus aureus Gram positive, and fungi (Candida albicans). Compounds (5, 7, and 8) indicated significant growth inhibition against E. coli Gram negative and fungi (C. albicans) with different inhibition zones starting from 7 to 17.5 mm.

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Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization, and Bioactivity Studies of the Schiff Base Ligand and its Zinc(II) Complex

Muhammad Salih

2024

ARO

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Theoretical and experimental investigation of N-alkyl substituted bis-imidazolium salts and their binuclear N-heterocyclic carbene silver acetate complexes

Yaqoob

Iqbal

Bhatti

et al. 2023

Journal of Coordination Chemistry

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The crystal structure of (E)-1-(((2-amino-4,5-dimethylphenyl)iminio)methyl)naphthalen-2-olate, C₁₉H₁₈N₂O

Xiong,

Zhang,

Zou

2024

Zeitschrift Für Kristallographie - New Crystal Structures

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Synthesis, crystal structure and antibacterial activity of zinc(II) complexes with Schiff bases derived from 5-fluorosalicylaldehyde

Cited by 3 publications

References 34 publications

Synthesis, Characterization, and Bioactivity Studies of the Schiff Base Ligand and its Zinc(II) Complex

Synthesis, Characterization, and Bioactivity Studies of the Schiff Base Ligand and its Zinc(II) Complex

Theoretical and experimental investigation of N-alkyl substituted bis-imidazolium salts and their binuclear N-heterocyclic carbene silver acetate complexes

The crystal structure of (E)-1-(((2-amino-4,5-dimethylphenyl)iminio)methyl)naphthalen-2-olate, C₁₉H₁₈N₂O

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Synthesis, crystal structure and antibacterial activity of zinc(II) complexes with Schiff bases derived from 5-fluorosalicylaldehyde

Cited by 3 publications

References 34 publications

Synthesis, Characterization, and Bioactivity Studies of the Schiff Base Ligand and its Zinc(II) Complex

Synthesis, Characterization, and Bioactivity Studies of the Schiff Base Ligand and its Zinc(II) Complex

Theoretical and experimental investigation of N-alkyl substituted bis-imidazolium salts and their binuclear N-heterocyclic carbene silver acetate complexes

The crystal structure of (E)-1-(((2-amino-4,5-dimethylphenyl)iminio)methyl)naphthalen-2-olate, C19H18N2O

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The crystal structure of (E)-1-(((2-amino-4,5-dimethylphenyl)iminio)methyl)naphthalen-2-olate, C₁₉H₁₈N₂O