Synthesis, crystal structure and antitumor activities of the dimeric silicotungstate containing cobalt: Na5K7[{β-SiCo2W10O36(OH)2(H2O)}2] ·39.5H2O

Tan, Rongxin; Pang, Xiaohong; Wang, Hui; Cui, Shuzhen; Jiang, Yunliang; Wang, Cheng; Wang, Xiaohong; Song, Wenzhi

doi:10.1016/j.inoche.2012.09.007

Cited by 12 publications

(6 citation statements)

References 40 publications

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“…130 The dinuclear polyoxometallate Na 5 K 7 [(b-SiCo 2 W 10 O 36 (OH) 2 (H 2 O)) 2 ]Á39.5H 2 O was synthesised and characterised by elemental analysis, IR spectroscopy, TGA, and X-ray crystallography. 131 In vitro antitumor studies showed that Na 5 K 7 -[(b-SiCo 2 W 10 O 36 (OH) 2 (H 2 O)) 2 ]Á39.5H 2 O exhibited remarkable inhibitory actions on liver cancer cells (SMMC-7721) and ovarian cancer cells (SK-OV-3). 131…”

Section: Tungstenmentioning

confidence: 99%

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Inorganic pharmaceuticals

Holder

2013

Annu. Rep. Prog. Chem., Sect. A: Inorg. Chem.

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This chapter reviews the literature reported during 2012 on some important advances in the area of inorganic pharmaceuticals. Research highlights for the respective metals during the year are also given. Highlights(I) A titanium(IV) which was highly toxic towards HeLa S3 and Hep G2 cancer cell lines, 1 (II) pharmacological studies of [bis(1,2-dimethyl-3-hydroxy-4-pyridinonato)oxovanadium(IV)], [VO(dmpp) 2 ] with fatty Zucker rats, 2 (III) the first X-ray crystal structures of nickel(II) and copper(II) salphen metal complexes bound to a quadruplex DNA, 3 (IV) evaluation of copper(II) complexes with thiosemicarbazone ligands as anti-cancer agents on human colon cancer and human breast cancer cell lines, 4 (V) the first report of ZnO nanoflowers that show significant proangiogenic properties as observed by in vitro and in vivo angiogenesis assays, 5 (VI) novel estradiol based metal complexes of 99m Tc as imaging agents for estrogen receptor (ER) positive breast tumours, 6 (VII) the use of [Ru(phen) 2 dppz] 2+ to study aggregation of a-synuclein (aS), which is associated with the development of Parkinson's disease, 7 and (VIII) the real-time monitoring of the caspase cascade in cancer cells during apoptosis with various caspase substrate-linked fluorescent proteins-conjugated gold nanoparticles as a new imaging probe.

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Section: Tungstenmentioning

confidence: 99%

“…131 In vitro antitumor studies showed that Na 5 K 7 -[(b-SiCo 2 W 10 O 36 (OH) 2 (H 2 O)) 2 ]Á39.5H 2 O exhibited remarkable inhibitory actions on liver cancer cells (SMMC-7721) and ovarian cancer cells (SK-OV-3). 131…”

Section: Tungstenmentioning

confidence: 99%

Inorganic pharmaceuticals

Holder

2013

Annu. Rep. Prog. Chem., Sect. A: Inorg. Chem.

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“…Polyoxometalates (POMs) are nanosized structures with potential chemical applications in catalysis, materials science, magnetism and medicine [10]. The structures of POMs may or may not contain heteroatoms, which divides this class of compounds into two groups: (1) the isopolianions of the formula (MmOy) xand (2) heteropolyanions of the formula (XnMmOy) x- [11].…”

Section: Introductionmentioning

confidence: 99%

Antifungal activity of silver salts of Keggin-type heteropolyacids against Sporothrix spp.

Mathias

Almeida

Passoni

et al. 2020

Journal of Microbiology and Biotechnology

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Sporotrichosis is a chronic and subacute mycosis causing epidemiological outbreaks involving sick cats and humans in southeastern Brazil. The systemic disease prevails in cats and in humans, with the symptoms restricted to the skin of immunocompetent individuals. Under these conditions, the prolonged treatment of animals and cases of recurrence justify the discovery of new treatments for sporotrichosis. This work addresses the antifungal activity of silver salts of Keggin-type heteropolyacid salts (Ag-HPA salts) such as Ag 3 [PW 12 O 40 ], Ag 6 [SiW 10 V 2 O 40 ], Ag 4 [SiW 12 O 40 ] and Ag 3 [PMo 12 O 40 ] and interactions with the antifungal drugs itraconazole (ITC), terbinafine (TBF) and amphotericin B (AMB) on the yeast and mycelia forms of Sporothrix spp. Sporothrix spp. yeast cells were susceptible to Ag-HPA salts at minimum inhibitory concentration (MIC) values ranging from 8 to 128 μg/ml. Interactions between Ag 3 [PW 12 O 40 ] and Ag 3 [PMo 12 O 40 ] with itraconazole and amphotericin B resulted in higher antifungal activity with a reduction in growth and melanization. Treated cells showed changes in cell membrane integrity, vacuolization, cytoplasm disorder, and membrane detachment. Promising antifungal activity for treating sporotrichosis was observed for the Ag-HPA salts Ag 3 [PMo 12 O 40 ] and Ag 3 [PW 12 O 40 ], which have a low cost, high yield and activity at low concentrations. However, further evaluation of in vivo tests is still required.

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“…This should be attributed to the synergism and enhancement effect of transition metals on the properties of POMs, especially the POMs of containing cobalts [12,13]. Therefore, substituting of multiple transition metals may be an effective way to tune properties of POMs for developing functional materials.…”

Section: Introductionmentioning

confidence: 99%

Tetra-cobalt-substiituted Dimeric Tungstoantimonate: Na10[Co4(H2O)10(B- -SbW9O33)2]�36H2O

Tan¹,

Xiao²,

Jin³

et al. 2015

Proceedings of the 2015 International Conference on Advanced Engineering Materials and Technology

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A new tetra-cobalt-substiituted dimeric tungstoantimonate Na 10 [Co 4 (H 2 O) 10 (B-β-SbW 9 -O 33 ) 2 ]·36H 2 O 1 was synthesized in a weakly alkaline solution. The compound was characterized by elemental analysis and IR spectroscopy. A single-crystal X-ray analysis was carried out on the crystal 1 which crystallizes in monoclinic system, space group P 21/n, with a = 12.529 Å, b = 12.778 Å, c = 29.434 Å, α = 90.000º, β = 101.158º , γ = 90.000º and Z = 2. Polyanion 1 consists of two B-β-SbW 9 units which are linked by four cobalt ions leading to a Keggin-type tetra-cobalt-substiituted dimeric structure.

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Synthesis, crystal structure and antitumor activities of the dimeric silicotungstate containing cobalt: Na5K7[{β-SiCo2W10O36(OH)2(H2O)}2] ·39.5H2O

Cited by 12 publications

References 40 publications

Inorganic pharmaceuticals

Inorganic pharmaceuticals

Antifungal activity of silver salts of Keggin-type heteropolyacids against Sporothrix spp.

Tetra-cobalt-substiituted Dimeric Tungstoantimonate: Na10[Co4(H2O)10(B- -SbW9O33)2]�36H2O

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