Synthesis, Crystal Structure, and Cytotoxiciy In Vitro of a Zinc(II) Complex

Abstract

A mononuclear zinc(II) complex, [ZnClL(N 3 )], where L is 1,2-diaminocyclohexane, was synthesized and characterized by elemental analysis, IR spectrum, and single-crystal X-ray diffraction. The crystal of the complex crystallizes in the monoclinic space group P2 1 /m, with unit cell dimensions a D 6.146 (2) A , b D 7.042(2) A , c D 12.498(3) A , b D 99.782(3) , V D 533.1(2) A 3 , Z D 2, R 1 D 0.0517, wR 2 D 0.1470. The Zn atom of the complex is in a tetrahedral coordination, with two N atoms of the ligand L, one azide N atom, and one Cl atom. The complex has moderate level of resistance against cell lines HeLa, Hep-G2, KB, and AGZY-83a.