Synthesis, crystal structure, magnetic property and nuclease activity of a new binuclear cobat(II) complex

Synthesis, crystal structure, and DNA cleavage activity of a dinuclear nickel(II) complex with a macrocyclic ligand

“…The band shows a bathochromic shift of about 38 nm and hypochromism of 23.4% after adding DNA. These findings support the hypothesis of a DNA intercalating interaction of the complex [24]. The value of K b was obtained from the ratio of slope to the intercept from the plot of [DNA]/(e a -e f ) versus [DNA] (Fig.…”

“…5, as 7.57 9 10 3 M -1 . The constant is smaller than those of DNA-intercalative complexes [6,24], so we deduce that the Ni(II) complex binds to DNA with a moderate intercalative mode. We have also investigated the DNA binding of the complex by circular dichroism spectroscopy.…”

A new self-assembled μ6-sulfato hexanuclear cobalt(II) complex of a symmetric dinucleating ligand: Synthesis and X-ray structural analysis

“…3. The average Co-Co separation in a dinuclear unit is 3.643 Å [22,27]. The average Co-Co separation where the two cobalt centers are interligand to each other is 3.122 Å.…”

DNA cleavage activities and mechanism of a novel heterodinuclear macrocyclic complex

“…The chemistry of multi-metal complexes as artificial nucleases has received much attention because of their generally higher DNA cleavage activity [1][2][3], and their importance in cancer therapy [4][5][6] and molecular biology [7,8]. According to the literatures, macrocyclic ligands with the rigid groups showed a better DNA cleavage ability after combining to the metal ions, because it may involve a synergistic mechanism among metal ions and rigid macrocyclic ligands [9].…”