Synthesis, electrochemical properties and fungicidal activity of 1,1′‐bis(aroyl)ferrocenes and their derivatives

Ferrocene in agriculture: from agrochemicals and soil remediation to selective chemosensors

“…1,1′-Disubstitued ferrocenes with different keto-ester, hydroxy-ester, and dihydroxy functionalities on both cyclopentadienyl rings were prepared (Figure 7 [21]) and assayed in vitro for antifungal activity against G. zeae, A. solani, C. arachidicola, P. piricola, and Fusarium oxysporum. The compounds showed relatively low fungicidal activity.…”

New examples of template catalysis based processes: glycerol-like units as efficient promoters for dehydrative nucleophilic substitutions of ferrocenylmethanol

“…1 The bio-organometallic chemistry of ferrocene based compounds with biomolecules 2 is also today intensively studied: 3,4 the main properties of the ferrocene unit in these compounds, related to their biological activity, are the small size, the high stability in aqueous and aerobic media, the relative lipophilicity, and the peculiar redox behavior. In the literature complex ferrocene derivatives with biological activity such as antifungal, [5][6][7][8][9][10][11][12][13] antimalerial, 14 anticancer, 15 antimicrobial, 16 anti-HIV-1, 17 antioxidant, 18 and PDE4 inhibitory activities 19 etc. are often reported, but it is important to underline that ferrocene itself exhibits interesting properties such as antianemic, 20 antiseptic, 21 or cytotoxic activities.…”

The synthesis, structural characterization and in vitro anti-cancer activity of novel N-(3-ferrocenyl-2-naphthoyl) dipeptide ethyl esters and novel N-(6-ferrocenyl-2-naphthoyl) dipeptide ethyl esters

“…A comprehensive review on the bioorganometallic chemistry of ferrocene has been published [6]. Examples of biologically active ferrocenyl derivatives encompass anti-bacterial [7][8][9], anti-fungal [10,11], anti-malarial [12][13][14][15] and anti-cancer therapeutic agents including ferrocifen [16][17][18][19][20][21][22][23][24][25].…”