Synthesis, <i>in vitro</i> macrophage response and detoxification of bamboo charcoal beads for purifying blood

Hsieh, Ming‐Fa; Wen, Hsiao‐Wei; Shyu, Chih-Liang; Chen, Szu-Hau; Li, Wen‐Tyng; Wang, Wei-Chieh; Chen, Wen‐Chi

doi:10.1002/jbm.a.32792

Cited by 7 publications

(3 citation statements)

References 19 publications

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“…Activated carbon can be used as an indigestible carrier to prevent the intake of toxic substances through the digestive tract, and thus bamboo charcoal powder is often used as an oral antidote to treat poisoning [ 15 ]. Therefore, bamboo charcoal and activated carbon have been widely used as adsorbents or detoxification agents in both animals and humans [ 16 , 17 ]. Previous studies have reported that dietary supplementation with bamboo charcoal has positive effects on animal growth, feed efficiency, specific growth rate, feed intake, nitrogen excretion, and digestion [ 15 , 18 , 19 , 20 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

Addition of Bamboo Charcoal to Selenium (Se)-Rich Feed Improves Growth and Antioxidant Capacity of Blunt Snout Bream (Megalobrama amblycephala)

Jiang

Lin

Miao

et al. 2021

Animals

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The ability of bamboo charcoal to reduce the negative effects of high dietary selenium (Se) concentrations was assessed by feeding juvenile blunt snout bream (Megalobrama amblycephala) one of five Se-rich diets (1.5 mg/kg Se; 36% protein, 8.7% lipid) containing graded levels (0–4 g/kg) of bamboo charcoal powder for eight weeks. There were four tanks (350 L) of fish (initial weight 16.0 ± 0.5 g) for each treatment, and the fish were fed to satiation four times each day. At the end of the feeding trial, all of the fish from each tank were weighed to calculate the growth performance. Blood samples were firstly obtained to collect plasma for the biochemical indexes determination. Liver tissues were then collected to determine the antioxidant enzyme activities and gene expression. Dorsal muscles were also collected to determine the nutrient composition. The results show that when the bamboo charcoal content in the Se-rich feed ranged between 0 and 3 g/kg, the weight growth rate (WGR) and specific growth rate (SGR) values increased with the higher dietary bamboo charcoal content, and the maximum WGR and SGR values were achieved when the bamboo charcoal content in the Se-rich feed was 2–3 g/kg (p < 0.05). The Se content in muscle tissues decreased significantly with the increased bamboo charcoal content (p < 0.05) in the Se-rich feed, which ranged from 0 to 4 g/kg. When the bamboo charcoal content in the Se-rich feed was 2–3 g/kg, the levels of glucose (GLU) and albumin (ALB) in plasma reached a maximum (p < 0.05), whereas the level of alkaline phosphatase (ALP) reached a minimum (p < 0.05). Additionally, the activities of catalase (CAT), total superoxide dismutase (T-SOD), total antioxidative capacity (T-AOC), and glutathione peroxidase (GSH-Px) were significantly enhanced (p < 0.05) when the bamboo charcoal content was 3 g/kg. In contrast, the malondialdehyde (MDA) level increased sharply when the bamboo charcoal content in the Se-rich feed was 1 g/kg, compared to the control group and the groups supplemented with 2–3 g/kg bamboo charcoal (p < 0.05). Regarding mRNA-level gene expression, the results show that dietary supplementation with 0 to 3 g/kg of bamboo charcoal increased the expression of keap1 and nrf2, whereas nfkb expression was inhibited (p < 0.05). The mRNA expression of the antioxidant enzymes cat, gpx, and mn-sod was consistently enhanced in the group fed with the 3 g/kg bamboo charcoal diet (p < 0.05). The expression of the pro-inflammatory cytokines tnfα and tgfβ was inhibited in the groups supplemented with 2–3 g/kg bamboo charcoal, whereas the expression of anti-inflammatory cytokines (il10) increased in the bamboo charcoal supplementation groups compared to the control group (p < 0.05). Generally, supplementation with 2–3 g/kg of bamboo charcoal in Se-rich feed improved the growth performance, physiological status, and antioxidant enzyme activities of blunt snout bream. Moreover, bamboo charcoal supplementation in Se-rich diets stimulated the antioxidant system and inhibited the inflammatory response by activating Nrf2-Keap1 and suppressing NF-κB.

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Section: Introductionmentioning

confidence: 99%

Addition of Bamboo Charcoal to Selenium (Se)-Rich Feed Improves Growth and Antioxidant Capacity of Blunt Snout Bream (Megalobrama amblycephala)

Jiang

Lin

Miao

et al. 2021

Animals

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“…These properties of bamboo charcoal make it a promising adsorbent material for enrichment and analysis of environmental pollutants [ 11 ]. The capability of bamboo charcoal for toxin adsorption has been reported in blood purification [ 12 , 13 ]. In addition, bamboo charcoal has uniform pore size (120–170 μm) and complete pore interconnectivity suitable for neobone ingrowth [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Poly(vinyl alcohol) Nanocomposites Reinforced with Bamboo Charcoal Nanoparticles: Mineralization Behavior and Characterization

2015

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Polyvinyl alcohol (PVA) demonstrates chemical stability and biocompatibility and is widely used in biomedical applications. The porous bamboo charcoal has excellent toxin absorptivity and has been used in blood purification. In this study, bamboo charcoal nanoparticles (BCNPs) were acquired with nano-grinding technology. The PVA and PVA/BCNP nanocomposite membranes were prepared and characterized by the tensile test, attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) and X-ray diffraction (XRD). Results showed that the tensile strength and elongation of the swollen PVA membranes containing 1% BCNPs (PB1) were significantly greater than those of PVA and other PVA/BCNP composite membranes. In addition, the major absorption band of OH stretching in the IR spectra shifted from 3262 cm−1 for PVA membrane containing 1% BCNP to 3244 cm−1 for PVA membrane containing 20% BCNP. This blue shift might be attributed to the interaction between the PVA molecules and BCNPs. Moreover, the intensity of the XRD peaks in PVA was decreased with the increased BCNP content. The bioactivity of the nanocomposites was evaluated by immersion in the simulated body fluid (SBF) for seven days. The mineral deposition on PB5 was significantly more than that on the other samples. The mineral was identified as hydroxyapatite (HA) by XRD. These data suggest that the bioactivity of the composite hydrogel membranes was associated with the surface distribution of hydrophilic/hydrophobic components. The PVA/BCNP composite hydrogels may have potential applications in alveolar bone regeneration.

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“…However, its surface strength is not good and it is hydrophobic. It does not have any antibacterial function, thus limiting biomedical applications such as blood purification, bone repair or replacement, and neuroprotection [ 8 , 9 , 10 , 11 ]. In recent years, to pursue a safer and healthier environment while using antimicrobial agents, in addition to the safety of use, the protection of the environment must also be considered [ 12 , 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Surface Modification of Bamboo Charcoal by O2 Plasma Treatment and UV-Grafted Thermo-Sensitive AgNPs Hydrogel to Improve Antibacterial Properties in Biomedical Application

Liu

Liao

2021

Nanomaterials

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With the advancement of science and modern medical technology, more and more medical materials and implants are used in medical treatment and to improve human life. The safety of invasive medical materials and the prevention of infection are gradually being valued. Therefore, avoiding operation failure or wound infection and inflammation caused by surgical infection is one of the most important topics in current medical technology. Silver nanoparticles (AgNPs) have minor irritation and toxicity to cells and have a broad-spectrum antibacterial effect without causing bacterial resistance and other problems. They are also less toxic to the human body. Bamboo charcoal (BC) is a bioinert material with a porous structure, light characteristics, and low density, like bone quality. It can be used as a lightweight bone filling material. However, it does not have any antibacterial function. This study synthesized AgNPs under the ultraviolet (UV) photochemical method by reducing silver nitrate with sodium citrate. The formation and distribution of AgNPs were confirmed by UV-visible spectroscopy and X-ray diffraction measurement (XRD). The BC was treated by O2 plasma to increase the number of polar functional groups on the surface. Then, UV light-induced graft polymerization of N-isopropyl acrylamide (NIPAAm) and AgNPs were applied onto the BC to immobilize thermos-/antibacterial composite hydrogels on the BC surface. The structures and properties of thermos-/antibacterial composite hydrogel-modified BC surface were characterized by Scanning Electron Microscopy (SEM), Fourier Transform Infrared spectrum (FT-IR), and X-ray photoelectron spectroscopy (XPS). The results show that thermos-/antibacterial composite hydrogels were then successfully grafted onto BC. SEM observations showed that the thermos-/antibacterial composite hydrogels formed a membrane structure between the BC. The biocompatibility of the substrate was evaluated by Alamar Blue cell viability assay and antibacterial test in vitro.

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Synthesis, in vitro macrophage response and detoxification of bamboo charcoal beads for purifying blood

Cited by 7 publications

References 19 publications

Addition of Bamboo Charcoal to Selenium (Se)-Rich Feed Improves Growth and Antioxidant Capacity of Blunt Snout Bream (Megalobrama amblycephala)

Addition of Bamboo Charcoal to Selenium (Se)-Rich Feed Improves Growth and Antioxidant Capacity of Blunt Snout Bream (Megalobrama amblycephala)

Poly(vinyl alcohol) Nanocomposites Reinforced with Bamboo Charcoal Nanoparticles: Mineralization Behavior and Characterization

Surface Modification of Bamboo Charcoal by O2 Plasma Treatment and UV-Grafted Thermo-Sensitive AgNPs Hydrogel to Improve Antibacterial Properties in Biomedical Application

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