Synthesis of 1,2,3-Triazole Derivatives from 2,3-Dienoates of Methyl Maleopimarate

Abstract

Hybrid compounds based on N-maleopimarimides containing a triazole-ring pharmacophore were prepared via 1,3-dipolar cycloaddition of methyl-2-azidoacetate to allenoates.

Kinetic study of the reaction of nucleophilic cyclopropanation of C60 fullerene with halogenated maleopimarimide

“…In conformity with the formulated goal and its solution, methane fullerenes with maleopimarimide fragments, which were not described in the scientific literature, have been chosen as test compounds. The synthesis of chloro‐ 3a–d and bromomethyl ketones 4a–d has been carried out on the basis of the previously obtained N ‐maleopyrimarimide‐substituted carboxylic acids 1a–d . Linear amino acids as starting ones were further converted into the spacer element, with the length of the carbon chain from n = 1 to n = 5.…”