Synthesis of 1,2,4-triazolo[5′,1′:2,3][1,3]thiazino[6,5-b]indol-10(5H)-ones based on 2-chloro-1H-indole-3-carbaldehyde

Vikrishchuk, N. I.; Tkachev, V. V.; Бородкин, Г. С.; Газиева, Галина А.; Шилов, Г. В.

doi:10.1016/j.tetlet.2020.152490

Cited by 4 publications

(2 citation statements)

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“…Huan Yan et al [51] reported a method to synthesize Indolesubstituted N-heterocyclic carbene ligands (175), 176 (a-d Natalia I. Vikrishchuk et al [52] developed a protocol for synthesis of new indole derivatives 180 (a-e) by reacting 2chloro-1H-indole-3-carbaldehydes 178 (a-b) with 179 (a-b) in the presence of DMF.…”

Section: Acid Followed By Refluxing For 1 H To Yield Final Compounds ...mentioning

confidence: 99%

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Insight into Indole‐Based Heterocyclic Scaffolds: A Medicinal Chemistry Perspective

Bendi,

Versha,

Rajni

et al. 2023

ChemistrySelect

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The importance of indole‐based heterocycle scaffolds in medicinal chemistry has increased as a result of their significant pharmacological and biological characteristics. These compounds′ importance in the discovery and creation of cutting‐edge medications to treat a variety of diseases is an instance of their worth. The current study highlights the numerous methods available to create different indole‐based heterocycle scaffolds and their favourable medical uses with the literature that has been published up to 2023.

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Section: Acid Followed By Refluxing For 1 H To Yield Final Compounds ...mentioning

confidence: 99%

“…Natalia I. Vikrishchuk et al [52] . developed a protocol for synthesis of new indole derivatives 180 (a–e) by reacting 2‐chloro‐1H‐indole‐3‐carbaldehydes 178 (a–b) with 179 (a–b) in the presence of DMF.…”

Section: Chemistry Of Indole Based Heterocycle Scaffoldsmentioning

confidence: 99%

Insight into Indole‐Based Heterocyclic Scaffolds: A Medicinal Chemistry Perspective

Bendi,

Versha,

Rajni

et al. 2023

ChemistrySelect

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Sc(OTf)₃‐Catalyzed Tunable Thio‐(3+3) Annulation Reactions of Indoline‐2‐thiones with α‐Benzylidene‐β‐tetralones

Jiang,

Ma,

Zhai

et al. 2024

Asian J Org Chem

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A Sc(OTf)3‐catalyzed tunable thio‐Michael addition/nucleophilic addition/dehydration reaction of indoline‐2‐thiones with α‐benzylidene‐β‐tetralones was realized, leading to biologically important tetrahydrobenzo[7,8]isothiochromeno[3,4‐b]indoles and thiazino[3,2‐a]indoles in moderate to good yields. Moreover, by extending the reaction time, the dehydrogenated cycloadducts dihydrobenzo[7,8]isothiochromeno[3,4‐b]indoles were also obtained from the reaction of indoline‐2‐thiones with α‐benzylidene‐β‐tetralones.

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The Molecular Diversity of 1H-Indole-3-Carbaldehyde Derivatives and Their Role in Multicomponent Reactions

et al. 2022

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Synthesis of 1,2,4-triazolo[5′,1′:2,3][1,3]thiazino[6,5-b]indol-10(5H)-ones based on 2-chloro-1H-indole-3-carbaldehyde

Cited by 4 publications

References 10 publications

Insight into Indole‐Based Heterocyclic Scaffolds: A Medicinal Chemistry Perspective

Insight into Indole‐Based Heterocyclic Scaffolds: A Medicinal Chemistry Perspective

Sc(OTf)₃‐Catalyzed Tunable Thio‐(3+3) Annulation Reactions of Indoline‐2‐thiones with α‐Benzylidene‐β‐tetralones

The Molecular Diversity of 1H-Indole-3-Carbaldehyde Derivatives and Their Role in Multicomponent Reactions

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Synthesis of 1,2,4-triazolo[5′,1′:2,3][1,3]thiazino[6,5-b]indol-10(5H)-ones based on 2-chloro-1H-indole-3-carbaldehyde

Cited by 4 publications

References 10 publications

Insight into Indole‐Based Heterocyclic Scaffolds: A Medicinal Chemistry Perspective

Insight into Indole‐Based Heterocyclic Scaffolds: A Medicinal Chemistry Perspective

Sc(OTf)3‐Catalyzed Tunable Thio‐(3+3) Annulation Reactions of Indoline‐2‐thiones with α‐Benzylidene‐β‐tetralones

The Molecular Diversity of 1H-Indole-3-Carbaldehyde Derivatives and Their Role in Multicomponent Reactions

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Product

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Sc(OTf)₃‐Catalyzed Tunable Thio‐(3+3) Annulation Reactions of Indoline‐2‐thiones with α‐Benzylidene‐β‐tetralones