Synthesis of 1(3H)-Iminobenzo[c]thiophene Derivatives by Hydriodic Acid-mediated Cyclization of 2-(Vinyl)thiobenzamide Derivatives

Synthesis of Spirocyclic Oxindole Dihydrothiophenes by DBU-Catalyzed [3 + 2] Annulation of Morita–Baylis–Hillman Carbonates with Isothiocyanates

“…More importantly, these spirocyclic oxindole dihydrothiophene compounds could be easily hydrolyzed and then converted into the corresponding dihydrothiophenone derivatives . The hydrolysis reaction proceeded smoothly and produced the desired product 5 in 86% yield in the presence of 10% hydrochloric acid and 1,2-dimethoxyethane (DME) (1:3, v/v) at reflux temperature for 1.5 h (Scheme ).…”

Hydriodic Acid‐Mediated Cyclization of α‐Substituted Secondary 2‐Ethenylbenzamides: Synthesis of 2‐Substituted 2,3‐Dihydro‐3,3‐dimethyl‐1H‐isoindol‐1‐ones and 3,3‐Disubstituted (E)‐1‐(Arylimino)‐1,3‐dihydroisobenzofurans

“…to Me 4 Si as internal standard, J in Hz. a-Substituted 2-Bromostyrenes 1a [6], 1b [7], 1c [7], 4a [8], 4b [9], 4c [10], and 4d [11] were prepared by the appropriate reported methods. All other chemicals used in this study were commercially available.…”