Synthesis of 1‐Acyl‐5‐amino‐4‐ethoxycarbonylpyrazoles from Monohydrazides of Cyclohexenedicarboxylic Acids and Ethyl Ethoxymethylenecyanoacetate.

Abstract

Ethoxymethylenecyanoacetate. -Both linear and cyclic products can be formed in the reaction of enol ester (II) with monohydrazides (I), depending on the reaction conditions. The stable, crystalline title pyrazoles (III), obtained in refluxing pyridine, yield amides (IV) in reactions with formamide and previously unreported cyclohexenecarboxylic acids (V) on alkaline hydrolysis. -(ZICANE, D.; TETERE, Z.; RAVINA, I.; PETROVA, M.; Chem.