Synthesis of 2-Aryl-4,5-diphenyl-1-(N-β-D-glucopyranosyl)imidazoles

Abstract

were prepared by the reaction between aromatic α-diketone (benzil), ammonium acetate and substituted arylaldehyde. These imidazoles were glucosylated using α-acetobromoglucose to form 2-aryl-4,5-diphenyl-1-(N-β-D-2,3,4,6-tetra-O-acetylglucopyranosyl)imidazoles (2a-g) which were deacetylated by sodium methoxide to afford 2-aryl-4, 5-diphenyl-1-(N-β-D-glucopyranosyl)imidazoles (3a-g). All synthesized compounds were characterized spectroscopically.