Synthesis of 2-Methoxy-4,6-Di(prop-1-Enyl)phenol From Eugenol and Its Activity as an Antioxidant

Abstract

Synthesis and antioxidant activity of 2-methoxy-4,6-di(prop-1-enyl) -metoksi-4,6-di(prop-1-enil) (68,04 ± 0,84% Keywords: Claisen rearrangement; DPPH; eugenol; isomerization; O-allylation ABSTRAK Sintesis dan uji aktivitas antioksidan senyawa 2-metoksi-4,6-di(prop-1-enil) fenol dari eugenol telah diteliti. Sintesis dilakukan melalui tiga tahap reaksi. Tahap pertama dilakukan reaksi O-alilasi terkatalisis misel CTAB terhadap eugenol pada suhu ruangan diperoleh 4-alil-1-(aliloksi)-2-metoksibenzena (2). Senyawa (2) selanjutnya dipanaskan dengan mengalami penataan ulang Claisen dan diperoleh 2,4-dialil-6-metoksifenol (3). Tahap akhir dilakukan isomerisasi dalam kondisi basa dalam pelarut etilen glikol terhadap senyawa (3)diperoleh 2

Role of surfactants on metal mediated cerium(IV) oxidation of valeraldehyde at room temperature and pressure

“…The rate of conversion increased with an increase in the surfactant concentration higher than CMC, and leveled off after the surfactant concentration reached 2CMC. Therefore, at high CTAB concentration, the rate of reaction increase gradually but it will be slowed down at 3.5 mM and the conversion of valeraldehyde did not change significantly [38]. Cetyltrimethylammonium bromide (CTAB, a representative cationic surfactant) is found to accelerate valeraldehyde oxidation path.…”