Synthesis of 25X-BOMes and 25X-NBOHs (X = H, I, Br) for pharmacological studies and as reference standards for forensic purposes

Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2AReceptor Agonists

“…The title compound was prepared according to reported conditions . Characterization was in accordance with reported values …”

“…10 Characterization was in accordance with reported values. 54 2-(4-Bromo-2,5-dimethoxyphenyl)ethan-1-amine Hydrochloride (3). The title compound was prepared according to reported conditions.…”

“…10 Characterization was in accordance with reported values. 54 3-(((4-Bromo-2,5-dimethoxyphenethyl)amino)methyl)phenol Hydrochloride (4a). The title compound was prepared according to General procedure A and in line with reported conditions, and the characterization was in accordance with reported values.…”

The new psychoactive substances 25H-NBOMe and 25H-NBOH induce abnormal development in the zebrafish embryo and interact in the DNA major groove

“…25H-NBOH and 25H-NBOMe used in this work were previously prepared by our research group, according to de Barros et al (2021b) . Fig.…”

Potential of chromatography and mass spectrometry for the differentiation of three series of positional isomers of 2‐(dimethoxyphenyl)‐N‐(2‐halogenobenzyl)ethanamines

“…These are positional isomers of compounds 1 , 7 , and 13 (Table 1), that are legally controlled in Russia 31 . The most known method 5,18,23,46 of the synthesis of N ‐(2‐substituted benzyl)phenethylamines consists in modification of the “classical” phenethylamines of the 2C family 47 by their reductive amination with the corresponding aldehydes. Synthesis of legally non‐controlled positional isomers of the NBOMe and NBF series was carried out according to a similar method from the corresponding phenethylamines with positional arrangement of methoxy groups different from 2,5‐ and was described earlier by our group 17,26 …”