Synthesis of 3-Arylcoumarins by FeCL3-Promoted Cyclization of orto-Methoxy-Substituted (E)-2,3-Diphenylpropenoic Acids or their Methyl Esters

Ge, H. Y.; Fang, Zhenggang; Qian, Bao-Hua

doi:10.1007/s10593-014-1442-2

Cited by 3 publications

(1 citation statement)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several trisubstituted acrylic acids within an aryl group at the position β have been efficiently obtained via one-pot reaction, a nickel-catalyzed arylcarboxylation of alkynes with arylmagnesium reagents and carbon dioxide (CO 2 , 1 atm) [60]. 3-Arylcoumarins have been also conveniently synthesized in excellent yields by a ferric chloride (FeCl 3 )-promoted tandem reaction using (E)-2,3diphenylpropenoic acids or their methyl esters [61]. Finally, an acrylonitrile derivative has also been synthesized with pyridinium hydrochloride, in the presence of silica gel, by using microwave irradiation [62].…”

Section: From Cinnamic Acidsmentioning

confidence: 99%

3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade

2021

View full text Add to dashboard Cite

3-Phenylcoumarins are a family of heterocyclic molecules that are widely used in both organic and medicinal chemistry. In this overview, research on this scaffold, since 2010, is included and discussed, focusing on aspects related to its natural origin, synthetic procedures and pharmacological applications. This review paper is based on the most relevant literature related to the role of 3-phenylcoumarins in the design of new drug candidates. The references presented in this review have been collected from multiple electronic databases, including SciFinder, Pubmed and Mendeley.

show abstract

Section: From Cinnamic Acidsmentioning

confidence: 99%

3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade

2021

View full text Add to dashboard Cite

show abstract

ChemInform Abstract: Synthesis of 3‐Arylcoumarins by FeCl₃‐Promoted Cyclization of orto‐Methoxy‐Substituted (E)‐2,3‐Diphenylpropenoic Acids or Their Methyl Esters.

Fang

Qian

2014

ChemInform

View full text Add to dashboard Cite

Palladium-Catalysed Intermolecular Direct C–H Bond Arylation of Heteroarenes with Reagents Alternative to Aryl Halides: Current State of the Art

Rossi

Ciofalo

2022

COC

View full text Add to dashboard Cite

This unprecedented review with 322 references provides a critical up-to-date picture of the Pd-catalysed intermolecular direct C–H bond arylation of heteroarenes with arylating reagents alternative to aryl halides that include aryl sulfonates (aryl triflates, tosylates, mesylates, and imidazole-1-sulfonates), diaryliodonium salts, [(diacetoxy)iodo]arenes, arenediazonium salts, 1-aryltriazenes, arylhydrazines and N’-arylhydrazides, arenesulfonyl chlorides, sodium arenesulfinates, arenesulfinic acids, and arenesulfonohydrazides. Particular attention has been paid to summarise the preparation of the various arylating reagents and to highlight the practicality, versatility, and limitations of the various developed arylation protocols, also comparing their results with those achieved in analogous Pd-catalysed arylation reactions involving the use of aryl halides as electrophiles. Mechanistic proposals have also been briefly summarised and discussed. However, data concerning Pd-catalysed direct C–H bond arylations involving the C–H bonds of aryl substituents of the examined heteroarene derivatives have not been taken into account.

show abstract

Synthesis of 3-Arylcoumarins by FeCL3-Promoted Cyclization of orto-Methoxy-Substituted (E)-2,3-Diphenylpropenoic Acids or their Methyl Esters

Cited by 3 publications

References 17 publications

3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade

3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade

ChemInform Abstract: Synthesis of 3‐Arylcoumarins by FeCl₃‐Promoted Cyclization of orto‐Methoxy‐Substituted (E)‐2,3‐Diphenylpropenoic Acids or Their Methyl Esters.

Palladium-Catalysed Intermolecular Direct C–H Bond Arylation of Heteroarenes with Reagents Alternative to Aryl Halides: Current State of the Art

Contact Info

Product

Resources

About

Synthesis of 3-Arylcoumarins by FeCL3-Promoted Cyclization of orto-Methoxy-Substituted (E)-2,3-Diphenylpropenoic Acids or their Methyl Esters

Cited by 3 publications

References 17 publications

3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade

3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade

ChemInform Abstract: Synthesis of 3‐Arylcoumarins by FeCl3‐Promoted Cyclization of orto‐Methoxy‐Substituted (E)‐2,3‐Diphenylpropenoic Acids or Their Methyl Esters.

Palladium-Catalysed Intermolecular Direct C–H Bond Arylation of Heteroarenes with Reagents Alternative to Aryl Halides: Current State of the Art

Contact Info

Product

Resources

About

ChemInform Abstract: Synthesis of 3‐Arylcoumarins by FeCl₃‐Promoted Cyclization of orto‐Methoxy‐Substituted (E)‐2,3‐Diphenylpropenoic Acids or Their Methyl Esters.