2017
DOI: 10.1007/s00044-017-1865-2
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Synthesis of 3-chloro-1-substituted aryl pyrrolidine-2,5-dione derivatives: discovery of potent human carbonic anhydrase inhibitors

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Cited by 23 publications
(17 citation statements)
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“…After this work, a single band was seen for each isoforms. In this procedure, the imaging way was applied out in 3% and 10% acrylamide for the stacking and the running gel with 0.1% SDS . Both CA isoforms activities were designated conforming to the procedure recorded by Verpoorte et al .…”
Section: Methodsmentioning
confidence: 99%
“…After this work, a single band was seen for each isoforms. In this procedure, the imaging way was applied out in 3% and 10% acrylamide for the stacking and the running gel with 0.1% SDS . Both CA isoforms activities were designated conforming to the procedure recorded by Verpoorte et al .…”
Section: Methodsmentioning
confidence: 99%
“…CA plays a very significant role in many more physiological processes including fluid secretion, acid–base balance, pH regulation, ion exchange, respiratory, lipogenesis, glycogenesis, ureagenesis, bone resorption, calcification, and transportation of CO 2 molecule from tissues to the lungs via blood, and gastric acid generation . The CA was systematized by seven historical irrelevant gene families including α‐, β‐, γ‐, δ‐, ζ‐, n‐, and θ‐CAs .…”
Section: Introductionmentioning
confidence: 99%
“…as described formerly. In this work, changes in absorbance were recorded during 3 min at 348 nm, where p‐nitrophenylacetate was used as a substrate, which was converted to the p‐nitrophenolate ion compound at both isoenzymes . For estimation of protein quantity, the Bradford method was used during the separation stages.…”
Section: Methodsmentioning
confidence: 99%