Synthesis of 3-Indolyl Perfluoroalkyl Carbinols by the Reaction of Indoles with Perfluorinated Aldehydes

Abstract

Perfluoroaliphatic aldehydes with different carbon chain length or their hemiacetals have been involved into selective non-catalytic hydroxyalkylation of indoles to produce the corresponding 3-indolyl perfluoroalkyl carbinols.