Synthesis of 6-(4-Chlorophenyl)-N-aryl-4-(trichloromethyl)-4H-1,3,5-oxadiazin-2-amines: A Comparative Evaluation of Dehydrosulfurization Methods of Starting 4-Chloro-N-(2,2,2 -trichloro-1-(3-arylthioureido)ethyl)benzamides

Synthesis, Spectral Characteristics, and Molecular Docking Studies of 2-(2,4-Dichlorophenoxy)-N-(2,2,2-trichloro-1-(3-arylthioureido)ethyl)acetamide

“…For example, effective inhibitors of the GADD34:PP1 holoenzyme complex, such as Salubrinal and Sal003 [13][14][15][16], as well as moderate inhibitors of some enzymes of the P450 family [17] and the hERG ion channel [18] are known among their structural analogs. In addition, these compounds are of interest for synthetic organic chemistry as substrates for the preparation of 4H-1,3,5-oxadiazine derivatives [19][20][21][22]. [23].…”