Synthesis of a novel cellulose nanowhisker-based drug delivery system

Dash, Rajalaxmi; Ragauskas, Arthur J.

doi:10.1039/c2ra01071b

Cited by 94 publications

(48 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several drug‐delivery systems based on nanocellulose materials for various pharmaceutical applications have been used in recent years . In one study, Trovatti et al .…”

Section: Advanced Nanocellulose Materials For Biomedical Applicationsmentioning

confidence: 99%

Recent advances in nanocellulose for biomedical applications

Jorfi

Foster

2014

J of Applied Polymer Sci

656

368

View full text Add to dashboard Cite

Nanocellulose materials have undergone rapid development in recent years as promising biomedical materials because of their excellent physical and biological properties, in particular their biocompatibility, biodegradability, and low cytotoxicity. Recently, a significant amount of research has been directed toward the fabrication of advanced cellulose nanofibers with different morphologies and functional properties. These nanocellulose fibers are widely applied in medical implants, tissue engineering, drug delivery, wound-healing, cardiovascular applications, and other medical applications. In this review, we reflect on recent advancements in the design and fabrication of advanced nanocellulose-based biomaterials (cellulose nanocrystals, bacterial nanocellulose, and cellulose nanofibrils) that are promising for biomedical applications and discuss material requirements for each application, along with the challenges that the materials might face. Finally, we give an overview on future directions of nanocellulose-based materials in the biomedical field.

show abstract

“…Several drug‐delivery systems based on nanocellulose materials for various pharmaceutical applications have been used in recent years . In one study, Trovatti et al .…”

Section: Advanced Nanocellulose Materials For Biomedical Applicationsmentioning

confidence: 99%

Recent advances in nanocellulose for biomedical applications

Jorfi

Foster

2014

J of Applied Polymer Sci

656

368

View full text Add to dashboard Cite

show abstract

“…Periodateoxidized polysaccharides have been used for a variety of biomedical applications such as wound care, [5,6] tissue engineering, [7][8][9] and drug delivery. [10][11][12]15] Apart from biomedical applications, periodate-oxidized polysaccharide products have been used as flocculating agents [34] and for ion-exchange separation. [35] A recent patent outlines the method for production of nonwoven fibrous mats with high wet and dry strength by crosslinking periodate-oxidized cellulose with transition metal containing crosslinking agents.…”

Section: Introductionmentioning

confidence: 99%

A UV-Vis Spectrophotometric Method for the Estimation of Aldehyde Groups in Periodate-Oxidized Polysaccharides Using2,4-Dinitrophenyl Hydrazine

Tummalapalli¹,

Gupta²

2015

Journal of Carbohydrate Chemistry

View full text Add to dashboard Cite

In this study, efforts have been made to develop a simple approach to determine aldehyde content in periodate-oxidized polysaccharides. A UV-Vis analytical technique using 2,4-dinitrophenylhydrazine (DNPH) was employed to calculate the aldehyde content. When tested against compounds like acetaldehyde and formaldehyde with known aldehyde content, the DNPH method yielded accurate results. The DNPH assay was Analysis of Aldehydes in Polysaccharides by UV-Vis 339further utilized to analyze the aldehyde generation during periodate oxidation of pectin, a naturally occurring plant polysaccharide. It was found that the DNPH assay was sensitive even at low concentrations of aldehyde and yielded accurate results. Therefore, this method could be used to control and optimize reaction parameters during the periodate oxidation of polysaccharides.

show abstract

“…To achieve controlled and rapid delivery of the targeting moiety, syringyl alcohol, a releasable linker, was then attached to it. The reported method could be widely adapted for the controlled delivery of enzymes, proteins and amine-containing drugs with the selection of desired linker molecules [179].…”

Section: Cnw Biodegradabilitymentioning

confidence: 99%

Functionalized Polymers from Lignocellulosic Biomass: State of the Art

Ten

Vermerris

2013

Polymers

View full text Add to dashboard Cite

Abstract:Since the realization that global sustainability depends on renewable sources of materials and energy, there has been an ever-increasing need to develop bio-based polymers that are able to replace petroleum-based polymers. Research in this field has shown strong potential in generating high-performance functionalized polymers from plant biomass. With the anticipated large-scale production of lignocellulosic biomass, lignin, cellulose and hemicellulosic polysaccharides will be abundantly available renewable feedstocks for biopolymers and biocomposites with physico-chemical properties that match or exceed those of petroleum-based compounds. This review examines the state of the art regarding advances and challenges in synthesis and applications of specialty polymers and composites derived from cellulose, hemicellulose and lignin, ending with a brief assessment of genetic modification as a route to tailor crop plants for specific applications.

show abstract

Synthesis of a novel cellulose nanowhisker-based drug delivery system

Cited by 94 publications

References 27 publications

Recent advances in nanocellulose for biomedical applications

Recent advances in nanocellulose for biomedical applications

A UV-Vis Spectrophotometric Method for the Estimation of Aldehyde Groups in Periodate-Oxidized Polysaccharides Using2,4-Dinitrophenyl Hydrazine

Functionalized Polymers from Lignocellulosic Biomass: State of the Art

Contact Info

Product

Resources

About