Synthesis of a polyaminocarboxylate-based aluminum complex and its structural studies using ¹H{¹³C}-HMBC NMR and a Karplus-type function

Abstract

The HBED chelator is used to stabilize small and hard metal ions such as Fe3+, Ti4+, Ga3+ and Al3+ in both medicine and industry. While the coordination of hexadentate HBED4-...

Latest developments in coumarin-based anticancer agents: mechanism of action and structure–activity relationship studies

“…32,33 It is worth noting that click chemistry has a wide application in medicinal chemistry. 34–37 The structure–activity relationship (SAR) studies showed that the 3-chloro and 4-methyl substituents in the coumarin moiety exhibited greater activity, whereas the 3-ethoxycarbonyl group in the coumarin ring exhibited reduced effectivity. It was also found that all these hybrids exhibited greater activity against the HT-29 cancer cell line under anoxic conditions.…”

One‐step hydrothermal synthesis of a green NiCo‐LDHs‐rGO composite for the treatment of lead ion in aqueous solutions

“…[ 30 ] Our group has been investigating the structural features of metal‐complex systems for a couple of years. [ 31 ]…”

“…[30] Our group has been investigating the structural features of metal-complex systems for a couple of years. [31] The synthesized NiCo-LDHs-rGO material was characterized by FESEM, EDX, mapping elemental analysis, FT-IR spectrophotometry, Brunauer-Emmett-Teller (BET), and XRD. According to the FESEM images of NiCo-LDHs-rGO (presented in Figure 2), spherical NiCo-LDHs microparticles have uniformly grown on the rGO nanosheets.…”

Alkoxy-functionalised dihydropyrimido[4,5-b]quinolinones enabling anti-proliferative and anti-invasive agents

“…6). 53,54 The characteristic proton (C-1, d) of the chiral carbon in 5a showed HMBC connection with C-10 ( δ 128.6), C-20 ( δ 168.0), C-17 ( δ 155.7), C-16 ( δ 139.1), C-5 ( δ 94.2), C-7 ( δ 118.2) and carbonyl carbon C-22 ( δ 181.4) (Fig. 2 and Fig.…”

“…52 It is worth noting that the HMBC technique is especially useful for distinguishing isomeric structures from each other (in our case 5 vs. 6). 53,54 The characteristic proton correlation with carbonyl carbons, indicating the angular structure of 6e.…”