Synthesis of a self-assembled copper(ii) metallo-rectangle with a guanosine-substituted terpyridine

Ghosh, Sushobhan; Silber, Georg; White, Andrew J. P.; Robertson, Neil; Vilar, Ramón

doi:10.1039/c3dt51845k

Cited by 9 publications

(10 citation statements)

References 25 publications

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“…was prepared by adding a DMSO solution of ligand 1 [27] to a stirred solution of Pd(NO3)2 in DMSO in 1:1 ratio. The product was precipitated by addition of acetone to the reaction mixture, filtered and re-dissolved in methanol.…”

Section: Synthesis and Characterization Of Metallo-rectangles 2a And mentioning

confidence: 99%

Assembly of Palladium(II) and Platinum(II) Metallo‐Rectangles with a Guanosine‐Substituted Terpyridine and Study of Their Interactions with Quadruplex DNA

Ghosh¹,

Mendoza²,

Cubo³

et al. 2014

Chemistry A European J

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Two novel [2+2] metallo-assemblies based on a guanosine-substituted terpyridine ligand (1) coordinated to palladium(II) (2 a) and platinum(II) (2 b) are reported. These supramolecular assemblies have been fully characterized by NMR spectroscopy, ESI mass spectrometry and elemental analyses. The palladium(II) complex (2 a) has also been characterized by single crystal X-ray diffraction studies confirming that the system is a [2+2] metallo-rectangle in the solid state. The stabilities of these [2+2] assemblies in solution have been confirmed by DOSY studies as well as by variable temperature (1)H NMR spectroscopy. The ability of these dinuclear complexes to interact with quadruplex and duplex DNA was investigated by fluorescent intercalator displacement (FID) assays, fluorescence resonance energy transfer (FRET) melting studies, and electrospray mass spectrometry (ESI-MS). These studies have shown that both these assemblies interact selectively with quadruplex DNA (human telomeric DNA and the G-rich promoter region of c-myc oncogene) over duplex DNA, and are able to induce dimerization of parallel G-quadruplex structures.

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Section: Synthesis and Characterization Of Metallo-rectangles 2a And mentioning

confidence: 99%

Assembly of Palladium(II) and Platinum(II) Metallo‐Rectangles with a Guanosine‐Substituted Terpyridine and Study of Their Interactions with Quadruplex DNA

Ghosh¹,

Mendoza²,

Cubo³

et al. 2014

Chemistry A European J

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“…Furthermore, while this Minireview has focussed on square planar metal ions, other systems with octahedral or square pyramidal metal ions have employed similar 2 , 2 or 1 , 3 strategies where the linking ligands occupy the four equatorial or basal sites of the metal ion, showing that the principles outlined in this Minireview are also applicable to other coordination geometries. It is our hope that the examples of structures and strategies given here for both 2 , 2 and 1 , 3 arrangements will encourage other chemists to explore these methods of assembling discrete metallosupramolecular systems.…”

Section: Resultsmentioning

confidence: 99%

Using Complementary Ligand Denticity to Direct Metallosupramolecular Structure about Metal Ions with Square‐Planar Geometry

Preston

Kruger

2020

ChemPlusChem

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An understanding of methods to control the structure of self‐assembled architectures is central to the efforts of chemists interested in self‐assembly synthesis. Metal ions with square‐planar geometry are a favorite of metallosupramolecular chemists, as there are only a limited number of possible ligand arrangements around the metal ion. Two such arrangements, firstly four monodentate donor sites (1,1,1,1), and secondly two monodentate donors and one bidentate donor (1,1,2) exemplify the symmetry interaction and ligand directed approaches, respectively. Symmetry interaction approaches using two bidentate sites (2,2) or a monodentate and tridentate site (1,3) have not received the same level of attention. In these arrangements, two complementary sites combine at the metal ion(s). This Minireview seeks to detail strategies employed to direct structure in systems with these arrangements, and is illustrated with key exemplars from the field.

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“…Furthermore, while this Minireview has focussed on square planar metal ions, other systems with octahedral or square pyramidal metal ions have employed similar 2,2 [49] or 1,3 [50] strategies where the linking ligands occupy the four equatorial or basal sites of the metal ion, showing that the principles outlined in this Minireview are also applicable to other coordination geometries. It is our hope that the examples of structures and strategies given here for both 2,2 and 1,3 arrangements will encourage other chemists to explore these methods of assembling discrete metallosupramolecular systems.…”

Section: Resultsmentioning

confidence: 99%

Cover Feature: (ChemPlusChem 5/2020)

Preston

Kruger

2020

ChemPlusChem

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The Cover Feature shows a jigsaw with some of the structures discussed in this Minireview. This overview details two of the less‐explored arrangements of ligands around square‐planar metal ions, and how they can be used to assemble exciting metallosupramolecular architectures. The Lego bricks symbolize the construction of complex structures from simple componentry. More information can be found in the Minireview by D. Preston and P. Kruger (DOI: 10.1002/cplu.202000019). The authors thank the Lego Group for allowing them to include the bricks in this image.

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Synthesis of a self-assembled copper(ii) metallo-rectangle with a guanosine-substituted terpyridine

Cited by 9 publications

References 25 publications

Assembly of Palladium(II) and Platinum(II) Metallo‐Rectangles with a Guanosine‐Substituted Terpyridine and Study of Their Interactions with Quadruplex DNA

Assembly of Palladium(II) and Platinum(II) Metallo‐Rectangles with a Guanosine‐Substituted Terpyridine and Study of Their Interactions with Quadruplex DNA

Using Complementary Ligand Denticity to Direct Metallosupramolecular Structure about Metal Ions with Square‐Planar Geometry

Cover Feature: (ChemPlusChem 5/2020)

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