Synthesis of a Sulfur-bridged Calixarene

Heteroatom-Bridged Calixarenes

“…[24] The reaction of dibromo derivatives of linear sulfur-bridged thiophenes with Na 2 S and copper salts in NMP as reported by Nakayama et al gave access to 46 in higher yield and gave larger thiacalixarenes 48. A simple extension of the previously described synthesis via 2,5-dilithiothiophenes to bis(electrophiles), such as SCl 2 yields thiacalix-[4]arene 46, although in very low yield (Scheme 15).…”

10.1007/s11176-008-2012-z

“…In the recent years, amino and sulfonamido enediyne ligands were also used to study metal-ion activation of Bergman cyclizations [102,103]. Macrocyclic enediynes 159, 162, and 170 having a rigid structure due to metal coordination at the nitrogen atoms were reported.…”

Heteroatom-Bridged Calixarenes

“…A simple extension of the previously described synthesis via 2,5-dilithiothiophenes to bis(electrophiles), such as SCl 2 yields thiacalix-[4]arene 46, although in very low yield (Scheme 15). [24] The reaction of dibromo derivatives of linear sulfur-bridged thiophenes with Na 2 S and copper salts in NMP as reported by Nakayama et al gave access to 46 in higher yield and gave larger thiacalixarenes 48. [25] Scheme 15.…”