SHORT COMMUNICATIONSIn recent time, the synthesis of symmetrical N-unsubstituted amino acetals of the general formula R 1 R 2 C(OR 3 NH 2 ) 2 has attracted increased attention. These compounds are used as the main acid-degradable unit of water-soluble polymers that are promising materials for targeted delivery of biologically active substances [1, 2], efficient gene transfection [3][4][5][6][7], and manufacture of recyclable environmentally safe thermosetting polymers [8,9].