Synthesis of acyl phosphatidylglycerol from phosphatidylglycerol in Escherichia coli K-12

Nishijima, Masahiro; Takao, Sa-Eki; Yumiko, Tamori; Doi, Osamu; Nojima, Shoshichi

doi:10.1016/0005-2760(78)90056-5

Cited by 19 publications

(2 citation statements)

References 30 publications

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“…the outer membrane lipase PldB involved in generating this donor (Nishijima et al, 1975;Hines and Xu, 2019). Indeed, the genome sequences of RCA isolates RCA23 and LE17 also contain a PldB homolog showing 30% sequence identity (e −20 ) to that of E. coli, suggesting that APG in RCA strains is synthesized in a similar manner.…”

Section: Resultsmentioning

confidence: 99%

Lipidomic Analysis of Roseobacters of the Pelagic RCA Cluster and Their Response to Phosphorus Limitation

et al. 2020

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The marine roseobacter-clade affiliated cluster (RCA) represents one of the most abundant groups of bacterioplankton in the global oceans, particularly in temperate and sub-polar regions. They play a key role in the biogeochemical cycling of various elements and are important players in oceanic climate-active trace gas metabolism. In contrast to copiotrophic roseobacter counterparts such as Ruegeria pomeroyi DSS-3 and Phaeobacter sp. MED193, RCA bacteria are truly pelagic and have smaller genomes. We have previously shown that RCA bacteria do not appear to encode the PlcP-mediated lipid remodeling pathway, whereby marine heterotrophic bacteria remodel their membrane lipid composition in response to phosphorus (P) stress by substituting membrane glycerophospholipids with alternative glycolipids or betaine lipids. In this study, we report lipidomic analysis of six RCA isolates. In addition to the commonly found glycerophospholipids such as phosphatidylglycerol (PG) and phosphatidylethanolamine (PE), RCA bacteria synthesize a relatively uncommon phospholipid, acylphosphatidylglycerol, which is not found in copiotrophic roseobacters. Instead, like the abundant SAR11 clade, RCA bacteria upregulate ornithine lipid biosynthesis in response to P stress, suggesting a key role of this aminolipid in the adaptation of marine heterotrophs to oceanic nutrient limitation.

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Section: Resultsmentioning

confidence: 99%