“…Among them, the Buchwald–Hartwig palladium-catalyzed cross-coupling of aryl halides with amines, the Ullmann-type copper-catalyzed cross-coupling of aryl halides with amines, and the Chan–Lam copper-mediated oxidative coupling of aryl metals with amines have proven to be powerful methods for C–N bond formation . An umpolung tactic, involving transition-metal-catalyzed amination of organometallic reagents with electrophilic aminating reagents (e.g., chloroamines and hydroxylamines), provides a valuable complementary approach . Indeed, various organometallic reagents are known to undergo electrophilic amination, including organomagnesiums, -zincs, -tins, -borons, , -silicons, and -titaniums .…”