Synthesis of analogs of pyridoxal 5'-phosphate

Pocker, Anna; Fischer, Edmond H.

doi:10.1021/bi00840a072

Cited by 33 publications

(17 citation statements)

References 24 publications

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“…When the ohydroxyl of PLP is methylated, the bands shift from 340 and 28911•25 to 313 and 279 nm. 26 When the o-hydroxyl of salicylaldehyde is methylated the band in dioxane shifts from 326 to 315 nm. 27 This band for the valine Schiff base of 3-hydroxy-4-pyridinecarboxaldehyde in methanol shifts from 323 to 310 nm for the 3-methoxy derivative.…”

Section: Resultsmentioning

confidence: 99%

Laser-induced reactions in pyridoxal catalysis

Ledbetter¹,

Askins²,

Hartman³

1979

J. Am. Chem. Soc.

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Section: Resultsmentioning

confidence: 99%

Laser-induced reactions in pyridoxal catalysis

Ledbetter¹,

Askins²,

Hartman³

1979

J. Am. Chem. Soc.

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“…These results suggest that the rates of the reconstitution are strongly affected by the ionization states of the cofactor. However, the rate constant for 3-O-MePLP, an active cofactor analogue binding to apophosphorylase in a similar binding mode to PLP (Shaltiel et al, 1969b;Feldmann & Helmreich, 1976), changed dependent on the same two pK values as PLP, although 3-O-MePLP has only a pK originating from the 5'phosphate group in the above pH range, its pA value due to the pyridine nitrogen being 4.15 (Pocker & Fischer. 1969).…”

Section: Resultsmentioning

confidence: 99%

Characterization of the pyridoxal phosphate site in glycogen phosphorylase b from rabbit muscle

Shimomura¹,

Fukui²

1978

Biochemistry

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“…Pyridoxal oxime (PLO) and pyridoxal-5'-phosphate (PLPO) were synthesised using a method used by Pocker et al (26).…”

Section: Reagentsmentioning

confidence: 99%

A comparative study of the electrochemical properties of vitamin B-6 related compounds at physiological pH

et al. 2011

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A comparative study of vitamin B6 group and related compounds in buffered solutions using electrochemical techniques has been performed at neutral pH. Irreversible bi-or tetraelectronic processes are observed for these substances, and the electron transfer coefficient (αn) calculated. It was concluded that either the first or second electron transfer were the rate determining step of the electrode process. The diffusion coefficient of these substances was calculated and the values given follow an inverse tendency to the molecular size. For aldehydes the values obtained were corrected of the hydration reaction.It is important to remark that catalytic waves were reported for the first time for these compounds. Using a model involving the nitrogen of the basic structure the kinetic constants were calculated for most of them.

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Synthesis of analogs of pyridoxal 5'-phosphate

Cited by 33 publications

References 24 publications

Laser-induced reactions in pyridoxal catalysis

Laser-induced reactions in pyridoxal catalysis

Characterization of the pyridoxal phosphate site in glycogen phosphorylase b from rabbit muscle

A comparative study of the electrochemical properties of vitamin B-6 related compounds at physiological pH

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