Synthesis of aromatic natural product frameworks using enyne metathesis

Rosillo, Marta; Casarrubios, Luis; Domı́nguez, Gema; Pérez‐Castells, Javier

doi:10.1016/s0040-4039(01)01313-2

Cited by 40 publications

(18 citation statements)

References 13 publications

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“…在 Pd 催化联烯胺环化的研究进展中, Grigg 课题组 [13] 在 1996 年报道了一例锡烷基化-碳钯化串联反应构建含氮、氧杂环的反应(Scheme 13). 转化经历联烯胺 α 位碳原子区域选择性环化, 得到中环(5～7)和大环 [23] 、自由基反应 [24] 、硅烷活化 [25] 、环丙烷化 [26] 、环丙烷差向异构化 [27] 、氧化 [28] 、氢化乙烯化 [29] 、[4＋2]环加成 [30] 、[3＋2]环加成 [31] 、[2＋2＋2]环加成 [32] 2012 年, Hsung 课题组 [43] Cat. (2 mol%) AgSgF 6 (2 mol%)…”

Section: Pd 催化联烯胺杂原子消除环化反应unclassified

Recent Advances on Transition-Metal-Catalyzed Allenamides Cyclization

Geng¹

2019

Chin. J. Org. Chem.

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With the especial reactivity, selectivity, availability and stability, the allenamides have got more and more attention, and the reports on allenamides cyclization grow rapidly. This review gives an up-to-date overview of transition-metal-catalyzed allenamides cyclization, which are sorted by metal catalysts in eight categories of Pd, Ru, Rh, Au, Co, Ag, Pt and Ni. For most of these transformations, the plausible mechanisms are demonstrated in details. Clarification of these issues is the key point for understanding the transition-metal-catalyzed allenamides cyclization and developing new high performance methodologies for chemists.

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Section: Pd 催化联烯胺杂原子消除环化反应unclassified

Recent Advances on Transition-Metal-Catalyzed Allenamides Cyclization

Geng¹

2019

Chin. J. Org. Chem.

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“…[50] The enyne metathesis was first outlined by Pérez-Castills et al, who showed that the various 1-ethynyl-2-(ω-alkenyl)-benzenes 56 (Scheme 21) could easily be converted into the vinyl-3,4-dihydronaphthalenes (and heteroanalogues) 57 in the presence of catalytic amounts of G I catalyst. [57] This approach was later extended by Hanzawa et al…”

Section: Metathesis Reactionsmentioning

confidence: 99%

Transition‐Metal‐Mediated or ‐Catalyzed Syntheses of Steroids and Steroid‐Like Compounds

2011

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“…As an extension of their previous contribution, in 1996 Mori and co-workers (428a) reported the first application of a ring-closing enyne metathesis reaction in a total synthesis, namely, that of the tricyclic alkaloid (À)-stemoamide in 9% overall yield (Scheme 44). Within this theme, natural products have more recently been constructed using Grubbs metathesis of aromatic enynes to produce 1,3-dienes that subsequently undergo a Diels-Alder reaction to give the desired product (440,441).…”

Section: B Intramolecular Ring-closing Enyne Metathesismentioning

confidence: 99%