Abstract:An efficient and convenient method for the synthesis of structurally unique and highly functionalized aryl 2-bromo-2-chloro-1,1-difluoroethyl ethers has been developed. This approach exhibited a broad reaction scope, simple operation, and no need for any expensive transition-metal catalysts, or highly toxic reagents. Notably, we demonstrated the potential utility of halothane for obtaining such aryl gem-difluoroalkyl ethers containing a bromochloromethyl group.
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.