Synthesis of asiatic acid derivatives and their cytotoxic activity

Synthesis and Cytotoxic Activity of Conjugates of Mitochondrial-Directed Cationic Compound F16 with Ursane-Structure Triterpenic Acids Containing a Polyhydroxylated A-ring

“…Ursolic acid was used as a reference compound. These phytochemicals possess a broad spectrum of beneficial biological properties, particularly their multifunctional anti-cancer activity and their capacity to trigger the mitochondrial pathway of apoptosis in a range of tumor cell types [4][5][6][7][8][9]. Furthermore, as an integral component of the diet, these triterpenoids could be used as preventive measures against human oncological diseases.…”

Influence of functional groups on properties of styrene grafted NR using glutaraldehyde as curing agent

“…Nowadays, natural rubber (NR) becomes an important elastomeric material due to various outstanding properties such as strength, resilience, elongation at break, and so forth . Furthermore, it is a natural product which is obtained from renewable resources.…”

“…Many research works have been carried out to overcome this drawback by modifying NR molecule. Many approaches on chemical modification have been reported, such as chlorination , epoxidation , hydrogenation , and grafting . However, graft copolymerization of NR with vinyl monomer is one of the most popular methods due to the ease of preparation.…”

“…It is reported that, the modified NR exhibited better performance when compared with the unmodified NR . Grafting of NR molecules is an emperical method to enhance the stability by using styrene (S) , maleic anhydride , methyl methacrylate (MMA) , acrylonitrile , vinyl acetate , and butyl acrylate . However, S and MMA are the most suitable monomers for grafting with NR as they provide a high grafting level .…”

“…However, S and MMA are the most suitable monomers for grafting with NR as they provide a high grafting level . The grafting reactions in NR latex system are mainly carried out by emulsion polymerization using redox initiators with various initiators . Emulsion polymerization is a more desirable approach as NR is naturally available in latex form and it would be very advantageous to perform grafting modification directly in the latex phase without using any organic solvents .…”