Synthesis of Benzenesulfonamide Derivatives via Ring Opening of Aziridines in the Presence of Magnetically Retrievable Graphene Based (CoFe@rGO) Nanohybrid

Abstract

Graphene based magnetic nanohybrids have engrossed considerable research curiosity because of their exceptional properties and diverse applications associated with green chemistry. In this regard, a practical, facile and regioselective preparation of 1,2-diamines from N-tosylaziridine/(S)-(+)-2-Benzyl-1-(ptolylsulfonyl)aziridine and aryl amines in the presence of magnetically separable graphene based nanohybrid (CoFe@rGO) has been proposed under mild and solvent free conditions. The FT-IR, FE-SEM, XRD and EDX spectroscopic analysis con rmed the formation of the CoFe@rGO nanohybrids. For unsymmetrical aziridine, nucleophilic attack of aryl amines was observed to take place selectively at the more substituted carbon atom of aziridine ring. Environmentally benign, e cient, shorter reaction time, solvent-free conditions, low catalyst loading, excellent reaction yields and reusability of the catalyst for six consecutive runs without signi cant loss in its activity are the key advantages of this protocol. HighlightsSynthesis of Graphene based magnetic nanohybrids (CoFe@rGO) using hydrothermal technique.Enhanced catalytic performance owing to large surface areas and active catalytic sites.Magnetically retrievable catalyst displaying great recyclability.Aziridine ring opening reactions with amines under solvent free conditions.