Among the various cross coupling reactions, CÀ C cross coupling reaction has attracted many researchers to investigate in the last four decades. The continuous, constant, and consistent progress in this field fetched a Noble prize in 2010, showing the importance of this reaction in diversified fields. Among the various transition metals studied for this reaction, Pd is one of the metals that has exhibited the highest activity due to its unique features and reactivity. Although Pd-based homogeneous catalyst was the preferred choice for many researchers, the field slowly diverted towards the development of Pd-based heterogeneous catalysts for CÀ C coupling reactions. This is obviously due to the high cost of Pd precursor, its selfdeactivation. In this context, metal organic frameworks (MOFs) are one of the solid catalysts frequently employed as host matrix for the deposition of Pd(II) salts and Pd nanoparticles. This is due to the widespread possibilities available for the functionalization of MOFs and their stability during the synthetic procedure. This review provides the design and development of Pd-based MOFs as heterogeneous catalysts for the CÀ C cross coupling reactions. After a brief introduction on MOFs and the importance of CÀ C coupling reactions, the main part of the review summarizes the catalytic data with respect to Pd(II) and Pd nanoparticles as active sites. The last section provides our views in this field for the further development in the near future. * Readily available reactants * Milder experimental conditions with high yields * Stability of catalysts in water * Reaction may be performed in aqueous and heterogeneous medium * Broad range of functional groups tolerance * High regio-/stereoselectivity * Small quantity of catalysts is sufficient * Applicable in one-pot synthesis * Easy separation boron compound (inorganic) * Environmentally friendly processThe recent advances in heterogeneous catalyst design for surpassing activity, selectivity and specially, stability of their homogeneous counterparts are based in the isolation of the Pd active sites in a solid support by anchoring through different type of bonds. [20][21][22][23][24][25][26][27] In this aspect, one of the solids that has [a] Dr.
