Synthesis of Bio-Inspired Silver Nanoparticles by Ripe and Unripe Fruit Extract of Tinospora cordifolia and Its Antioxidant, Antibacterial and Catalytic Studies

Kanagala, Praveena; Gaddam, Susmila Aparna; Gunji, Priyanka; Kotakadi, Venkata Subbaiah; Kalla, Chandra Mouli; Vijaya, Tartte; Gopal, D. V. R. Sai

doi:10.5101/nbe.v12i3.p214-226

Cited by 9 publications

(12 citation statements)

References 35 publications

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“…A higher proportion was 50 nm, and most of the particles appeared spherical, and few were polygonal in shape ( Figure 3 B). Indeed, other researchers [ 26 ] and [ 27 ] have also reported similar results regarding the shape and size of the nanoparticles from the TEM analyses. The smaller size and spherical shape exhibited by the Ca-AgNPs are generally desirable for biomedical applications such as drug delivery.…”

Section: Resultssupporting

confidence: 70%

Characterization and Therapeutic Applications of Biosynthesized Silver Nanoparticles Using Cassia auriculate Flower Extract

Sabapathi

Ramalingam

ArulJothi

et al. 2023

Plants

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The current study analyzes the biosynthesis of silver nanoparticles using the Cassia auriculate flower extract as the reducing and stabilizing agent. The Cassia auriculate- silver nanoparticles (Ca-AgNPs) obtained are characterized by UV–Vis spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM) analysis. The results of the spectral characterization have revealed that the surface Plasmon resonance band observed at 448 nm confirms the formation of AgNPs. TEM analysis of the Ca-AgNPs was a predominately spherical shape with a size assortment of 30 to 80 nm and an angular size of 50 nm. The well-analyzed Ca-AgNPs were used in various biological assays, including healthcare analysis of antimicrobial, antioxidant (DPPH), and cytotoxic investigations. Ca-AgNPs showed efficient free radical scavenging activity and showed excellent antimicrobial activity against to pathogenic strains. The occurrence of Ca-AgNPs lead to reduced Live/Dead ratio of bacteria (from 36.97 ± 1.35 to 9.43 ± 0.27) but improved the accumulation of bacterial clusters. The cytotoxicity of Ca-AgNPs was carried out by MTT assay against MCF-7 breast cancer cells and a moderate cytotoxic. The approach of flower extract-mediated synthesis is a cost-efficient, eco-friendly, and easy alternative to conventional methods of silver nanoparticle synthesis.

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Section: Resultssupporting

confidence: 70%

Characterization and Therapeutic Applications of Biosynthesized Silver Nanoparticles Using Cassia auriculate Flower Extract

Sabapathi

Ramalingam

ArulJothi

et al. 2023

Plants

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“…So, green synthesis of AgNPs is presently a very much attentive research field due to its easy, fast, and eco-friendly method without involving the utilization of organic solvents and perilous chemicals and outlay to be efficient when compared with chemical and physical methods 6 , 7 . In addition, the plant based green synthesis is the finest candidate for wide-ranging fabrication of nanoparticles with controlled shape and size, however green synthesized nanoparticles comprise and detected to be irregular in size and shape in majority of the cases 8 , 9 . The bioactive phyto-constituents like polyphenols and other bio-constituents like flavinoids, tannins, alkaloids, saponins and glycosides, found in various parts of plants leaves, fruits, seeds, stem, bark and roots, are extensively used for biosynthesis of metal nanoparticles, which actively participate in reduction and stability of nanoparticles.…”

Section: Introductionmentioning

confidence: 99%

Multifaceted phytogenic silver nanoparticles by an insectivorous plant Drosera spatulata Labill var. bakoensis and its potential therapeutic applications

Gaddam

Kotakadi

Subramanyam

et al. 2021

Sci Rep

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The current investigation highlights the green synthesis of silver nanoparticles (AgNPs) by the insectivorous plant Drosera spatulata Labill var. bakoensis, which is the first of its kind. The biosynthesized nanoparticles revealed a UV visible surface plasmon resonance (SPR) band at 427 nm. The natural phytoconstituents which reduce the monovalent silver were identified by FTIR. The particle size of the Ds-AgNPs was detected by the Nanoparticle size analyzer confirms that the average size of nanoparticles was around 23 ± 2 nm. Ds-AgNPs exhibit high stability because of its high negative zeta potential (− 34.1 mV). AFM studies also revealed that the Ds-AgNPs were spherical in shape and average size ranges from 10 to 20 ± 5 nm. TEM analysis also revealed that the average size of Ds-AgNPs was also around 21 ± 4 nm and the shape is roughly spherical and well dispersed. The crystal nature of Ds-AgNPs was detected as a face-centered cube by the XRD analysis. Furthermore, studies on antibacterial and antifungal activities manifested outstanding antimicrobial activities of Ds-AgNPs compared with standard antibiotic Amoxyclav. In addition, demonstration of superior free radical scavenging efficacy coupled with potential in vitro cytotoxic significance on Human colon cancer cell lines (HT-29) suggests that the Ds-AgNPs attain excellent multifunctional therapeutic applications.

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“…Presently, green synthesis of metal nanoparticles using various parts of plants, their extracts act as reducing agent for generation of metal nanoparticles. The previous reports on biosynthesis of AgNPs and PVP coated AgNPS by various plant extracts like seed extract of Annona squamosa L, Ficus fruit extract, Terminalia belarica and Capsicum annuum L. revealed similar type of results regarding SPR of both coated and uncoated AgNPs [24,[26][27][28].…”

Section: Uv-visible Spectral Analysis Of Ff-agnps and Pvp-ff-agnpsmentioning

confidence: 76%

“…The antibacterial efficiency of bio-synthesized FF-AgNPs and PVP-FF-AgNPs were determined against four bacterial strains of both gram negative bacteria such as Escherichia coli, Pseudomonas aeruginosa and gram positive such as Staphylococcus aureus and Bacillus megatorium, by using Agar discdiffusion method as described by Kotakadi et al [23][24][25]. Different concentration of biosynthesized FF-AgNPs and PVP-FF-AgNPs were loaded on 5 mm of sterile Whatman No 1 filter paper discs as follows 25 micrograms (25 mcg), 50 mcg, 75 mcg and 100 mcg.…”

Section: Antimicrobial Activity Of Ff-agnps and Pvp-ff-agnpsmentioning

confidence: 99%

“…The shape of silver nanoparticles also plays prominent role in antimicrobial property. Similarly various biosynthesised AgNPs using by various plant extracts exhibited very good antibacterial activities on both gram negative and gram positive bacteria [11,[23][24]27]. Similarly the PVP coated biosynthesised AgNPs also exhibit very good antibacterial activity on both gram negative and gram positive bacteria [32][33][34].…”

Section: Antimicrobial Activity Of Ff-agnps and Pvp-ff-agnpsmentioning

confidence: 99%

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Dual Degradation of Hexavalent Chromium (VI) and Cotton Blue Dye by Reduced and PVP-capped Silver Nanoparticles Using Fruit Extract of Ficus carica

Narjala¹,

Gaddam²,

Casimeer³

et al. 2022

Nano BioMed ENG

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Recent investigations on green synthesis of silver nanoparticles (AgNPs) have been widely used in various therapeutic and industrial applications. So in the present study, AgNPs and PVP coated AgNPs were biosynthesized using fig fruit (Ficus carica) named as FF-AgNPs PVP-FF-AgNPs. The FF-AgNPs and PVP-FF-AgNPs revealed the surface Plasmon resonance band at 446 nm and 460 nm respectively. The FT-IR analysis of both nanoparticles reveals that different bioactive components of the fruit extract were actively involved in reduction of AgNPs. The SEM revealed that the particles are roughly spherical and irregular in shape and size, EDX analysis confirms the formation of complete reduction of silver to elemental silver. DLS studies also revealed similar results with both the nanoparticles are within the range of 10 ± 5 nm to 35 ± 5 nm. The zeta potential studies reveal negative potential values were as follows FF-AgNPs has -13.8 mV and PVP-FF-AgNPs has -17.1 mV. They also exhibit good antimicrobial activity. Another important application of these nanoparticles is dual detection of toxic chromium (VI) and photocatalytic dye degradation of cotton blue by H 2 O 2 quenching and without quenching. It is concluded that, biosynthesized FF-AgNPs and PVP-FF-AgNPs have multiple applications of economic importance and environmental pollution.

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Synthesis of Bio-Inspired Silver Nanoparticles by Ripe and Unripe Fruit Extract of Tinospora cordifolia and Its Antioxidant, Antibacterial and Catalytic Studies

Cited by 9 publications

References 35 publications

Characterization and Therapeutic Applications of Biosynthesized Silver Nanoparticles Using Cassia auriculate Flower Extract

Characterization and Therapeutic Applications of Biosynthesized Silver Nanoparticles Using Cassia auriculate Flower Extract

Multifaceted phytogenic silver nanoparticles by an insectivorous plant Drosera spatulata Labill var. bakoensis and its potential therapeutic applications

Dual Degradation of Hexavalent Chromium (VI) and Cotton Blue Dye by Reduced and PVP-capped Silver Nanoparticles Using Fruit Extract of Ficus carica

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