Synthesis of bisnitroepoxides and their applications in the synthesis of bis(thiazolidine-2-thiones), bis(dithiocarbamates), bis(xanthates) and bis(thiazoles)

Abstract

Novel bis (nitroepoxides) were prepared based on terephthaldehyde and isophthaladehyde and their reactions with diversities of nucleophiles such as primary and secondary amine-based dithiocarbamic acids, xanthates, and ammonia-based dithiocarbmamates were investigated for the synthesis of bis (thiazolidine-2-thiones), bis (dithiocarbamates), bis (xanthates) and bis (thiazoles), respectively. It provides simple access to complex molecules in one step in high to excellent yields. Supplementary Information The online version contains supplementary material available at 10.1038/s41598-024-74156-3.