Synthesis of C,N,N-Cyclometalated Gold(III) Complexes with Anionic Amide Ligands

Abstract

A series of neutral C,N,N Au(III) complexes was synthesized with N-(8-quinolinyl)benzamide derivatives and chiral N-(2-(oxazolin-2-yl)phenyl)benzamide derivatives. This convenient synthesis method for amide ligands as well as an operationally simple complexation by direct C-H auration permitted changes to both the steric and electronic properties of the Au(III) complexes for promoting catalytic three-component coupling of an aldehyde, an amine, and an alkyne.