Synthesis of cadmium sulfide-tungsten trioxide nanocomposites for photo-catalytic degradation of organic pollutants and growth retardation of waterborne bacteria and biofilms

Synthesis of indole-based oxadiazoles and their interaction with bacterial peptidoglycan and SARS-CoV-2 main protease: In vitro, molecular docking and in silico ADME/Tox study

“…The antibiofilm potential of each compound was quantitatively investigated against P. aeruginosa and MRSA strains by using microtitre culture plate assay [ [33] ]. Briefly, 20 µl fresh cultures of P. aeruginosa and MRSA strains (1x 10 7 CFU/ml) were added into 180 µl of increasing concentrations of each compound (0.25–4 mg/ml) in a 96 well sterile polystyrene flat bottom microtitre plate and were incubated without shaking at 37°C for 24 h. After 24 h of incubation, bacterial suspensions from each well were completely decanted and the wells were washed twice with sterile phosphate buffer saline (PBS, 1X) and left for complete air drying.…”