Synthesis of carbon-11 labeled fluorinated 2-arylbenzothiazoles as novel potential PET cancer imaging agents

Synthesis, Biological Activity and Recent Advancement of Benzothiazoles: A Classical Review

“…The amino, hydroxyl, and chloro group containing benzothiazole shows better anticancer activity. [17] 2. The substituents at second position of benzothiazole ring like mercapto group and hydrazine group are responsible for marked bactericidal activity and anti-inflammatory activity.…”

“…[2] Benzothiazole is a privileged bicyclic ring system with multiple applications. They show numerous biological activities such as antimicrobial [3][4][5][6][7] , anticancer [8][9][10][11] , anthelmintic [12] , and anti-diabetic activities. [13] They have also found applications in industry as anti-oxidants, vulcanization accelerators.…”

Nano-graphene oxide composite for in vivo imaging

“…C (t ½ 20 minutes), and 64 Cu (t ½ 12.7 hours). 4,8,9 However, the limited t ½ of such radiotracers (typically only a few hours) necessitates dose-on-demand production at manufacturing sites in close proximity to the PET scanners. Therefore, the synthesis of PET radiotracers does not fit the typical drugmanufacturing paradigm.…”

Syntheses and Characterizations of Some New N-alkyl, Isoxazole and Dioxazole Derivatives of 5-Chloroisatin

“…The usage of some isatin derivatives for antibacterial, antimalarial, antiproliferative and anti-coagulant [4][5][6][7][8][9], antimicrobial, anticonvulsative, anticancer, antiHIV, etc. activities and also antifungal, herbicidal agents [10][11][12][13][14][15][16][17].Many other remarkable applications are reported in the literature, such as the selective inhibition of corrosion in mild steel by 5- [18,19]. These 5-Chloroisatin derivatives were synthesized using Nalkylation reaction under catalysis by phase transfer [20][21][22][23].…”