Synthesis of chiral tripodal receptors under solvent-free conditions using microwave irradiation for investigation of anion and cation recognition properties

Abstract

Amide based chiral tripodal receptor derivatives were synthesized under microwave irradiation in quite high yields (76%-84%) and they were characterized by IR and 1D, 2D, 1 H-and 13 C-NMR spectroscopies. The recognition properties of these tripodal receptors towards some anions and organic ammonium salts were investigated by 1 H-NMR titration in DMSO-d 6 . The tripodal (S)-phenyl receptor demonstrated a highly significant enantiomeric selectivity towards the (S)-(-)-1-phenyletylammonium perchlorate (ERF= 91.74 S).