Synthesis of continuously substituted quinolines from o-alkenyl aromatic isocyanides by palladium-catalyzed intramolecular imidoylative 6-endo cyclization

Abstract

An efficient synthesis of continuously substituted quinoline derivatives via palladium-catalyzed intramolecular 6-endo imidoylative cyclization of o‐alkenyl aryl isocyanides with (hetero)aryl halides or vinylic triflates has been developed. The reaction proceeds...