Synthesis of Cyclic β-1,6-Oligosaccharides by Electrochemical Polyglycosylation of glucosamine monomers

Abstract

Synthesis of protected precursors of cyclic β-1,6-oligoglucosamines by electrochemical polyglycosylation of thioglycosides as a monomer is performed. The monomer with 2,3-oxazolidinone protecting group afforded the cyclic disaccharide exclusively. Cyclic oligosaccharides up to trisaccharide were obtained using the monomer with 2-deoxy-2-azido group.