Synthesis of fused quinazolinones via visible light induced cyclization of 2-aminobenzaldehydes with tetrahydroisoquinolines

Abstract

This study reports a novel method for the synthesis of fused quinazolinone by the visible-light-induced cyclization of 2-aminobenzaldehyde and tetrahydroisoquinoline. The reaction was carried out under different experimental conditions and...

Visible light-mediated synthesis of quinazolinones from benzyl bromides and 2-aminobenzamides without using any photocatalyst or additive

“…Jiangxi Province Key Laboratory of Synthetic Chemistry, East China University of Technology, Nanchang, 330013, China. E-mail: zbxie@ecut.edu.cn visible light has a wide range of practical applications in the fields of organic synthetic chemistry [36][37][38][39][40][41] and photocatalytic composite materials. 42,43 Inspired by recent photochemical studies, we report a new approach for the green synthesis of quinazolinones using benzyl bromide and 2-aminobenzamide under mild conditions without additives, oxidants, or catalysts.…”

“…In recent years, visible light has been successfully utilized as a clean energy source with high sustainability and environmental friendliness. Researchers have found that visible light has a wide range of practical applications in the fields of organic synthetic chemistry 36–41 and photocatalytic composite materials. 42,43 Inspired by recent photochemical studies, we report a new approach for the green synthesis of quinazolinones using benzyl bromide and 2-aminobenzamide under mild conditions without additives, oxidants, or catalysts.…”