Synthesis of G0 aminopolyol and aminosugar dendrimers, controlled by NMR and MALDI TOF mass spectrometry

Abstract

Organic compounds designed to serve as stable dendrimer cores were developed. A series of aminosugar and amino polyol containing G0 dendrimers were synthesized. The reaction mixture composition was checked by MALDI TOF mass spectrometry, while that of purified products – by 1H and 13C NMR combined with 2D NMR spectroscopy as well as MALDI TOF MSMS mass spectra. Mass spectrometric fragmentation experiments were performed in positive ion mode in order to determine common fragmentation patterns of [M+H]+ ions.

Review of photoresponsive and glycoside dendrimers in biomaterials and sensors applications

“…28. [85][86][87] A summary of selected types of dendrimers and applications referenced is found in Table 1 below.…”

Role of Cyclodextrin Cross-Linker Type on Steroid Hormone Micropollutant Removal from Water Using Composite Nanofiber Membrane

“…Despite the widespread use of EP for βCD cross-linking, its toxicity and carcinogenicity have been documented, , rendering it unsuitable for water treatment applications. Consequently, alternative and more biocompatible cross-linkers have been reported in the literature for βCD cross-linking. − Triphenylolmethane triglycidyl ether (TMTE) and trimethylolpropane triglycidyl ether (TPTE) have been selected in this study as alternative cross-linkers based on characteristics of lower toxicity, commercial availability, and similar epoxy groups suitable for cross-linking reactions, as present in EP. − TMTE and TPTE have been reported as cross-linkers in biomaterials including dental materials − and drug delivery materials. , Chung et al reported TMTE cross-linked photocurable material that aimed to be applied in dental applications showing low curing shrinkage, low water sorption, and low water solubility. Suner et al reported the biomaterials containing TPTE, which showed fast enzymatic degradation of 80–90% using pectinase and amyloglucosidase.…”