Synthesis of Hydrophilic Epoxy-Functionalized Films by UV-Initiated Copolymerization

Abstract

Bisphenol A based epoxy acrylate (BABEA), a commercial ultraviolet (UV)-curiable material, was introduced as a new manufacturing material for facile fabrication of epoxy-functionalized films through UV-initiated copolymerization using glycidyl methacrylate (GMA) as the functional monomer. X-ray photoelectron spectroscope (XPS) results indicated the existence of epoxy groups on the surface of the poly (BABEA-co-GMA), which allowed for binding protein through an epoxy-amino group reaction. The contact angel results indicated the poly (BABEA-co-MMA) is hydrophilic, which avoided nonspecific adsorption of biological species. Bovine serum albumin (BSA) was successfully immobilized on the poly (BABEA-co-GMA) films by using the introduced epoxy groups effectively. This makes it possible to extend the application of such films in the fields of bio-separations and bio-recognitions.