The paper describes experimental approaches to measuring key nuclear astrophysical reactions involving radioactive isotopes. Specifically the paper considers the utilisation of (d,n) and (d,p) transfer reactions to probe the strengths of key resonances in the hydrogen burning/proton capture reactions 30 P(p,γ) and 26 Al(p,γ). The use of a radioactive target and silicon strip detector set-ups to study the key 26 Al(n,p) and (n,α) destruction reactions relevant to explosive burning conditions in core collapse supernovae is also reported.