Synthesis of lauryl grafted sodium alginate and optimization of the reaction conditions

Yang, Jisheng; He, Wen

doi:10.1016/j.ijbiomac.2011.12.027

Cited by 38 publications

(7 citation statements)

References 21 publications

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“…In recent past, attempts have also been made to prepare amphiphilic lauryl-alginate conjugates. However, the physicochemical characterization has not proved any beneficial effect or biomedical implications 14 , 15 .…”

Section: Resultsmentioning

confidence: 99%

Preparation of Lauroyl Grafted Alginate-Psyllium Husk Gel Composite Film with Enhanced Physicochemical, Mechanical and Antimicrobial Properties

Fernandes

Acharya

Bhatt

2018

Sci Rep

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In this study, a lauroyl grafted hydrophobic glycolipid derivative of alginate has been successfully synthesized and characterized. This glycolipid has been incorporated into Psyllium husk gel-alginate composite films and compared with the films containing only Psyllim husk gel and Psyllim husk gel-alginate for its mechanical and physicochemical properties. Additionally, the composite film has also been evaluated for protein adsorption and antimicrobial property to verify its utility in biomedical applications. The results showed that the composite films have enhanced physicochemical and mechanical properties. The film produced better swelling characteristic and lower protein adsorption property indicating the usefulness of the film in wound care dressing, particularly for low suppurating wounds. Incorporation of the synthesised glycolipid derivative also imparts antimicrobial activity to the composite film. Therefore, the developed film is capable of sustaining the microbial contamination during the storage and also valuable in the biomedical utility including wound dressings.

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Section: Resultsmentioning

confidence: 99%

Preparation of Lauroyl Grafted Alginate-Psyllium Husk Gel Composite Film with Enhanced Physicochemical, Mechanical and Antimicrobial Properties

Fernandes

Acharya

Bhatt

2018

Sci Rep

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“…As described in Scheme , Alg‐β‐CD was prepared according to the literature with some improvements. NaAlg (0.4 g) was partially protonated in 50 mL of DMF containing 0.5 g TSA by stirring at 50 °C for 30 min.…”

Section: Methodsmentioning

confidence: 99%

Synthesis of beta‐cyclodextrin‐grafted‐alginate and its application for removing methylene blue from water solution

Yang

Han

et al. 2014

J of Chemical Tech & Biotech

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BACKGROUND Beta‐cyclodextrin (β‐CD) has a hydrophilic exterior and a hydrophobic internal cavity which gives it the ability to form a host–guest complex. Sodium alginate (NaAlg) is a natural polysaccharide which can form a hydrogel in the presence of divalent cations. RESULTS The degree of substitution (DS) of the resulting β‐CD grafted alginate was 12%. The adsorption ratio of β‐CD to methylene blue (MB) was close to 2:1 which agreed with the theoretical value. The inclusion property of the Alg‐β‐CD/MB‐Ca hydrogel was excellent and stable. The hydrogel could be disintegrated easily with the aid of Na2CO3, and the Alg‐β‐CD sol obtained could be reused. CONCLUSION This study indicated that the method of aggregation–disintegration of the prepared hydrogel used to adsorb MB from water was effective and could be reused. © 2014 Society of Chemical Industry

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“…Grafting with other polymers gives it a better mechanical and sustained-release abilities. Carrying cells and factors enhance repair functions [ 70 , 71 , 72 ].…”

Section: Directional Modifications Of Three Polymersmentioning

confidence: 99%

Three Polymers from the Sea: Unique Structures, Directional Modifications, and Medical Applications

Wang

Qin

2021

Polymers

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With the increase of wounds and body damage, the clinical demand for antibacterial, hemostatic, and repairable biomaterials is increasing. Various types of biomedical materials have become research hotspots. Of these, and among materials derived from marine organisms, the research and application of alginate, chitosan, and collagen are the most common. Chitosan is mainly used as a hemostatic material in clinical applications, but due to problems such as the poor mechanical strength of a single component, the general antibacterial ability, and fast degradation speed research into the extraction process and modification mainly focuses on the improvement of the above-mentioned ability. Similarly, the research and modification of sodium alginate, used as a material for hemostasis and the repair of wounds, is mainly focused on the improvement of cell adhesion, hydrophilicity, degradation speed, mechanical properties, etc.; therefore, there are fewer marine biological collagen products. The research mainly focuses on immunogenicity removal and mechanical performance improvement. This article summarizes the source, molecular structure, and characteristics of alginate, chitosan, and collagen from marine organisms; and introduces the biological safety, clinical efficacy, and mechanism of action of these materials, as well as their extraction processes and material properties. Their modification and other issues are also discussed, and their potential clinical applications are examined.

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Synthesis of lauryl grafted sodium alginate and optimization of the reaction conditions

Cited by 38 publications

References 21 publications

Preparation of Lauroyl Grafted Alginate-Psyllium Husk Gel Composite Film with Enhanced Physicochemical, Mechanical and Antimicrobial Properties

Preparation of Lauroyl Grafted Alginate-Psyllium Husk Gel Composite Film with Enhanced Physicochemical, Mechanical and Antimicrobial Properties

Synthesis of beta‐cyclodextrin‐grafted‐alginate and its application for removing methylene blue from water solution

Three Polymers from the Sea: Unique Structures, Directional Modifications, and Medical Applications

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