Synthesis of magnetic nanoparticles and their application to bioassays

Abstract

Magnetic nanoparticles have been attracting much interest as a labeling material in the fields of advanced biological and medical applications such as drug delivery, magnetic resonance imaging, and array-based assaying. In this review, synthesis of iron oxide magnetic nanoparticles via a reverse micelle system and modification of their surface by an organosilane agent are discussed. Furthermore, as a practical biological assay system, the magnetic detection of biomolecular interactions is demonstrated by using the combination of a patterned substrate modified with a self-assembled monolayer and the magnetic nanoparticles.

A Review: Biological Synthesis Of Silver and Copper Nanoparticles

“…In the current context, importance is being given to the fabrication of a wide range of nanomaterials for developing environmentally benign technologies in material synthesis [12]. Despite of their minute structure, they trigger the chemical activity due to their distinctive crystallographic nature that increases surface area, hence the scope of reactivity [13,14]. In recent times, synthesis of inorganic nanoparticles has been demonstrated by many physical and chemical means.…”

A novel amperometric catechol biosensor based on α-Fe2O3 nanocrystals-modified carbon paste electrode

“…Nanosized particles of magnetite and NiCuZn-doped magnetites were prepared by coprecipitation and sol-gel combustion methods by Aphesteguy et al and studied for effects of the doping cations on the morphology, structure, and magnetic properties of the resulting spinel to be used in above applications. Nanostructured haematite (a-Fe 2 O 3 ) is another prominent iron oxide phase useful in biomedicine and clinical diagnosis due to its stability under physiological conditions (Laurent et al 2008, Osaka et al 2006 From the viewpoint of the applied research, different forms of iron (III) oxides are some of the most commonly investigated and used metal oxides for various environmental and industrial applications. As NCs, iron oxide exhibits unique functional features that strongly differ from those of well-crystallized particles and find important applications in nanoelectronic devices, information storage, magnetocaloric refrigeration, color imaging, bioprocessing, ferrofluid technology, and catalysis (Zboril et al 2002).…”

Decoration of multiwalled carbon nanotubes with protected iron nanoparticles

“…Methods include: decomposition [8], microwave-hydrothermal [9], ultra-sonication assisted [10], hydrolysis of iron chloride [11], gas-liquid interfacial synthesis [12], the reverse micelle method [13], laser pyrolysis [14], laser ablation [15] and liquid-solid-solution [16]. They are also a result of high iron loading in carbon nanotube (CNT) synthesis [17] and similar results can be achieved by filling CNTs [18,19].…”