Synthesis of MgO Nanoparticles from Different Organic Precursors; Catalytic Decontamination of Organic Pollutants and Antitumor Activity

Moustafa, Islam M. I.; Saleh, Ihab A; Abdelhami, Mohamed R

doi:10.4172/2169-0022.1000359

Cited by 5 publications

(2 citation statements)

References 23 publications

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“…Considering that the obtained IC 50 values are generally lower than those reported in the literature [2,47] and given that the lower the IC 50 value is, the greater the effect of the compounds is [47], the MgO NPs under this study can be considered very effective in terms of the cytotoxicity and proliferation inhibition of cancer cells, which are also able to preserve the healthy cells.…”

Section: Mg(oh)2 → Mgo + H2omentioning

confidence: 73%

MgO Nanoparticles Obtained from an Innovative and Sustainable Route and Their Applications in Cancer Therapy

Daniele,

Volpe,

Cesare

et al. 2023

Nanomaterials

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This paper aimed to evaluate the biological damages towards diseased cells caused by the use of MgO nanoparticles (NPs). The NPs are produced by a calcination process of a precursor, which is an aqueous suspension of nanostructured Mg(OH)2, in turn synthesized following our original, time-energy saving and scalable method able to guarantee short times, high yield of production (up to almost 10 kg/week of NPs), low environmental impact and low energy demand. The MgO NPs, in the form of dry powders, are organized as a network of intercrystallite channels, in turn constituted by monodispersed and roughly spherical NPs < 10 nm, preserving the original pseudo hexagonal-platelet morphology of the precursor. The produced MgO powders are diluted in a PBS solution to obtain different MgO suspension concentrations that are subsequently put in contact, for 3 days, with melanoma and healthy cells. The viable count, made at 24, 48 and 72 h from the beginning of the test, reveals a good cytotoxic activity of the NPs, already at low MgO concentrations. This is particularly marked after 72 h, showing a clear reduction in cellular proliferation in a MgO-concentration-dependent manner. Finally, the results obtained on human skin fibroblasts revealed that the use MgO NPs did not alter at all both the vitality and proliferation of healthy cells.

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Section: Mg(oh)2 → Mgo + H2omentioning

confidence: 73%

MgO Nanoparticles Obtained from an Innovative and Sustainable Route and Their Applications in Cancer Therapy

Daniele,

Volpe,

Cesare

et al. 2023

Nanomaterials

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“…Several different synthesis methods provide MgO nanoparticles, including hydrothermal and sol‐gel process, chemical and plasma‐enhanced chemical vapor deposition (CVD, PECVD), vapor‐liquid‐solid (VLS), pulsed laser deposition (PLD), laser ablation, molecular beam epitaxy (MBE), sputtering, and electrospinning method . These methods often require high temperature, time or sophisticated and expensive apparatus, limiting the yield of the process and, especially, the ability to scale‐up the production of the MgO nanoparticles.…”

Section: Introductionmentioning

confidence: 99%

MgO nanoparticles synthesized starting from an innovative one‐step process

2017

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Nanosized MgO is a functional material showing a great promise as destructive adsorbent for toxic chemical agents, unique optical electronic, magnetic, thermal, and mechanical properties, as well as in good bactericidal performance in aqueous environments and in the cancer therapy. In this study, MgO nanoparticles are obtained by thermal decomposition of nanosized Mg(OH) 2 , which are synthesized by means of an innovative, time and cost-effective, scalable, and patented method.The nanoparticles are characterized by means of several techniques such as thermal analyses, X-ray diffraction analysis, infrared spectroscopy, transmission electron microscopy, atomic force microscopy, and surface area measurements (BET).After a pseudomorphic decomposition of the hydroxide precursor, pure and crystalline MgO nanoparticles are obtained. These nanoparticles are roughly spherical, monodispersed, and monocrystalline, having size ≤10 nm. Moreover, they exhibited a surface area up to 178 m 2 /g, revealing a bimodal mesoporous distribution with the important part of the pores with dimensions peaked at 4.87 nm. K E Y W O R D Smagnesium oxide, nanoparticles, synthesis, transmission electron microscopy

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Biosynthesis of magnesium oxide nanoparticles using Hagenia abyssinica female flower aqueous extract for characterization and antibacterial activity

Hirphaye,

Bonka,

Tura

et al. 2023

Appl Water Sci

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The present study deals with the biosynthesis of magnesium oxide nanoparticles using the Hagenia abyssinica female flower aqueous extract. The prepared MgO NPs were characterized by visual observation, UV–Vis, XRD, FTIR, and SEM studies. Optimum parameters such as plant extract volume (25 mL), temperature (60 ℃), pH (12), precursor concentration (1 mM), reaction time (120 min), and the formation of the MgO NPs in the colloidal solution were monitored by a UV–Vis spectrophotometer. XRD patterns of MgO NPs confirmed the face-centered cubic structure and average crystallite size of NPs at 12.8 nm. The FTIR spectra depicted a peak at 407 cm−1, which corresponds to the stretching vibration of MgO and is the characteristic peak for MgO NPs. SEM confirms spherical morphology, and the overall size of MgO NPs ranges from 10 to 40 nm. The antibacterial activity of synthesized MgO NPs was determined by the agar-well-diffusion method, which found that nanoparticles have significant antibacterial activity zone of inhibition against Staphylococcus aureus (27 ± 0.28 mm) and against Escherichia coli (15 ± 0 mm).

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Synthesis of MgO Nanoparticles from Different Organic Precursors; Catalytic Decontamination of Organic Pollutants and Antitumor Activity

Cited by 5 publications

References 23 publications

MgO Nanoparticles Obtained from an Innovative and Sustainable Route and Their Applications in Cancer Therapy

MgO Nanoparticles Obtained from an Innovative and Sustainable Route and Their Applications in Cancer Therapy

MgO nanoparticles synthesized starting from an innovative one‐step process

Biosynthesis of magnesium oxide nanoparticles using Hagenia abyssinica female flower aqueous extract for characterization and antibacterial activity

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