Synthesis of N-vinyl-2-pyrrolidone-based branched copolymers via crosslinking free-radical copolymerization in the presence of a chain-transfer agent

Abstract

Branched copolymers are synthesized via the crosslinking free radical copolymerization of N vinyl 2 pyrrolidone and dimethacrylates of various structures that is conducted in the presence of the chain transfer agent 1 decanethiol. The kinetics of this process and the composition of the products are stud ied by IR spectroscopy, and the content of pendant C=C bonds is estimated. Correlations between the con tent of dimethacrylate monomer units in the copolymer and the rate of discoloration of a photochromic probe (6 nitrospiropyran) incorporated into the product are established.

Structure and State of Water in Branched N-Vinylpyrrolidone Copolymers as Carriers of a Hydrophilic Biologically Active Compound

“…A 3D copolymer structure was formed after the polymerization of dimethacrylate as more active comonomer [ 44 ]. It contained pendant double bonds that mainly attached PVP chains.…”

“…We synthesized amphiphilic copolymers of VP with dimethacrylates [ 44 ] that were excellent precursors to form biologically active compound (BAC) nanostructures [ 45 , 46 , 47 , 48 ]. They have low cytotoxicity and are able to penetrate into cells [ 46 ].…”

Synthesis and characterization of C60 -based composites of amphiphilic N -vinylpyrrolidone/triethylene glycol dimethacrylate copolymers

“…The comonomer TEGDM acts as a branching agent because of double bonds in the side chains involved in the polymer chains growth. Their topological structure (the length of the primary and cross‐site polymer chains, the number of branches) depends on the ratio [VP]:[TEGDM]:[DT], the propagation rate constant k p and the chain transfer constant k tr to the DT . With increasing of branching agent content the length of cross‐site chains decreases, and a number of branches grows.…”

“…With increasing of the TEGDM content in copolymer and, accordingly, DT the portion of low‐molecular weight component grows (to compare the curves for the B5 and B12). The reason is the reaction of chain transfer , which restricts the growth of polymer chains …”

“…The copolymers of VP and triethylene glycol dimethacrylate (TEGDM) obtained by radical copolymerization in toluene with and without of 1‐decanethiol (DT) by the method described in Ref. were used. At the molar ratio [VP]:[TEGDM]:[DT] 100:5:0, 100:5:5, 100:12:12, the B0, B5, and B12 (the number in the notation of (co)polymer corresponds to the DT amount in the reaction mixture VP‐TEGDM‐DT) copolymers were obtained, respectively.…”