Synthesis of New 2-(1,3-Dithianyl)phenols and Hexakis-[p-(1,3-dithian-2-yl)phenoxy]cyclotriphosphazene

Abstract

2-Chloro-1,3-dithiane was obtained by the chlorination of 1,3-dithiane with N-chlorosuccinimide. Reactions of 2-chloro-1,3-dithiane with various substituted phenols lead to 2-(1,3-dithianyl)phenols (3). Hexakis-[p-(1,3-dithian-2-yl)phenoxy]cyclotriphosphazene (6) was obtained by reaction with hexachlorotriazacyclotriphosphazene (5).

Synthesis, structural characterization and anti-carcinogenic activity of new cyclotriphosphazenes containing dioxybiphenyl and chalcone groups

“…The synthesis of different phosphazene compounds has been reported [13,[45][46][47][48][49][50][51][52][53] but there are only four articles about synthesis of the phosphazene compounds bearing chalcone groups [10,[54][55][56], there are, however, no studies about synthesis of dioxybiphenyl substituted chalcone-cyclophosphazene compounds. The cyclotriphosphazenes bearing 2,2 0 -dihydroxybiphenyl are much more stable to hydrolysis and thermal decomposition than hexachlorocyclotriphosphazene [1].…”

Iron-Catalyzed Radical Oxidative Coupling Reaction of Aryl Olefins with 1,3-Dithiane

“…As shown in Table , FeCl 3 was utilized as the catalyst in the presence of 2,3-dichloro-5,6-dicyano-1,4-benzoqinone (DDQ) and gave little to no desired product in these reactions. Since 2-H-1,3-dithiane is sparingly stable in an FeCl 3 catalyst system, after some experimentation, we reasoned that use of an initiator might be beneficial and N -chlorosuccinimide (NCS) was necessary to facilitate the coupling in a preactivation step . To our delight, upon warming to 0 °C, the aggregates 2-chloro-1,3-dithianes appear to disappear and 1,3-dithiane is efficiently converted with 2a to furnish the desired product 3a in 75% yield (Table ).…”