Synthesis of New 2-Amino-3-(2-Oxothiazol-Methyl)-Substituted-1,4-Naphthoquinone Derivatives Based on Silica Nanoparticles as a Reusable Heterogeneous Catalyst

Farahani, Hassan Vasheghani; Bayat, Mohammad; Nasri, Shima

doi:10.1007/s12633-019-0098-z

Cited by 6 publications

(2 citation statements)

References 27 publications

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“…Farahani et al 69 utilized silica-based materials to develop an environmentally friendly approach for the synthesis of potentially biologically active molecular scaffolds. They employed a one-pot, three-component reaction involving 2-hydroxy-1,4-naphthoquinone ( 1 ), 2-aminothiazole ( 124 ), and aromatic aldehydes 123a – k , facilitated by nano-SiO 2 (20% mol) as a Lewis acid and heterogeneous nanocatalyst in acetonitrile at room temperature.…”

Section: Synthetic Developments On 2-hydroxy-14-naphthoquinonementioning

confidence: 99%

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Recent Advances in the Synthesis of 2-Hydroxy-1,4-naphthoquinone (Lawsone) Derivatives

Sagar,

Shankar,

Khanna

et al. 2023

SynOpen

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Lawsone, also known as 2-hydroxy-1,4-naphthoquinone, has been extensively studied and found to be a crucial precursor in the production of a diverse range of natural products like molecular scaffolds, which are highly sought after for biological research purposes. Due to its unique chemical composition, Lawsone has been utilized for over a century as a starting material for the synthesis of numerous biologically active molecules and materials, showcasing intriguing properties across a wide range of scientific and technological applications. Additionally, Lawsone has been widely used in organic synthesis processes, with its various applications. The recent advances in the synthesis of different scaffolds starting from Lawsone and their applications are being discussed in details in the current review covering the literature during the period of 2017-2023.

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Section: Synthetic Developments On 2-hydroxy-14-naphthoquinonementioning

confidence: 99%

“…The structures of the synthesized molecules were determined using spectroscopic techniques (Scheme 39 ). 69…”

Section: Synthetic Developments On 2-hydroxy-14-naphthoquinonementioning

confidence: 99%